What should I do if my Omnipod (insulin pump) falls off?

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Last updated: November 24, 2025View editorial policy

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Immediate Action for Omnipod Detachment

Replace the Omnipod immediately with a new pod and transition to multiple daily injections (MDI) with long-acting basal insulin if a replacement pod is not immediately available to prevent diabetic ketoacidosis and severe hyperglycemia. 1

Immediate Steps When Pod Falls Off

First Priority: Prevent Hyperglycemia and DKA

  • Check blood glucose immediately using a fingerstick meter, as you have lost all insulin delivery and are at risk for rapid glucose elevation 1
  • Administer correction insulin via injection (rapid-acting insulin pen or syringe) if blood glucose is elevated, as the pod failure represents complete interruption of insulin infusion 1
  • Monitor for ketones if blood glucose exceeds 250 mg/dL (14 mmol/L), as infusion set failures are the "Achilles heel" of pump systems and can rapidly lead to ketoacidosis 1

Second Priority: Restore Insulin Delivery

  • Apply a new Omnipod as soon as possible if replacement pods are available 1
  • If no replacement pod is immediately available, transition to MDI using your backup insulin supplies (this is why backup supplies are essential) 1
  • Calculate basal insulin needs from your previous pump settings: sum your 24-hour basal rates and administer as long-acting insulin (glargine or detemir) while waiting for pod replacement 2
  • Continue rapid-acting insulin for meals and corrections using your insulin-to-carbohydrate ratios and correction factors from your pump settings 2

Common Causes of Pod Detachment

Technical and Environmental Factors

  • Adhesive failure from exposure to water, sweat, oils, or lotions at the insertion site 1
  • Environmental conditions including high temperatures, humidity, or physical activity that compromises adhesion 1
  • Mechanical trauma from clothing, seatbelts, or accidental bumping that dislodges the pod 1
  • Inadequate skin preparation before pod application, leaving oils or moisture that prevent proper adhesion 1

Skin-Related Issues

  • Contact dermatitis (irritant or allergic) from adhesive components, which may cause inflammation and compromise pod adherence 1
  • Lipohypertrophy at overused sites, creating an uneven surface that prevents proper pod adhesion 3

Prevention Strategies for Future Pod Loss

Optimize Pod Adhesion

  • Prepare skin thoroughly by cleaning with alcohol and allowing complete drying before pod application 1
  • Rotate insertion sites systematically every 2-3 days to prevent lipohypertrophy and maintain healthy skin for optimal adhesion 3
  • Consider adhesive reinforcement with additional medical tape or barrier products if you experience frequent pod detachment, particularly during exercise or in hot weather 1
  • Avoid applying lotions or oils near the pod site, as these compromise adhesive integrity 1

Maintain Backup Supplies

  • Always carry backup insulin supplies including long-acting basal insulin, rapid-acting insulin, syringes or pens, and blood glucose testing supplies 1
  • Keep extra pods readily available and ensure you can obtain replacements promptly through your supplier 1
  • Have a written backup plan that includes your basal rates, insulin-to-carbohydrate ratios, and correction factors for transitioning to MDI 1

When to Contact Healthcare Provider or Manufacturer

Contact Manufacturer Technical Support If:

  • Pods repeatedly fall off before the expected 3-day wear time, as this may indicate a manufacturing defect requiring replacement 1
  • You notice pod malfunction such as occlusion alarms, cracked housing, or insulin delivery issues prior to detachment 1
  • Skin reactions develop including severe redness, itching, or contact dermatitis that prevents pod use 1

Contact Healthcare Provider If:

  • Blood glucose remains elevated above 250 mg/dL despite correction insulin, or ketones are present, indicating possible DKA 1
  • You experience recurrent pod failures requiring adjustment of insertion sites or adhesive strategies 1
  • Signs of infection develop at insertion sites, including erythema, warmth, purulent drainage, or fever 3

Critical Safety Considerations

  • Never attempt to reattach a detached pod, as this creates infection risk and cannot guarantee proper insulin delivery 1
  • Report device failures to the manufacturer and FDA MAUDE database to ensure safety monitoring and potential recalls are appropriately tracked 1
  • Recognize that pod detachment represents complete insulin delivery interruption, requiring the same urgent response as any pump failure with immediate transition to alternative insulin delivery 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Management of Insulin for Patients on Insulin Pump Requiring TPN

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Managing Pooling Sensation with Medication Pumps

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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