Does magnesium supplementation improve sleep quality?

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Last updated: April 2, 2025View editorial policy

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From the Research

Magnesium supplementation, specifically Magnesium-L-threonate, can significantly improve sleep quality, especially deep and REM sleep stages, as well as mood, energy, alertness, and daily activity and productivity, as evidenced by a recent randomized controlled trial 1.

Key Findings

  • The study found that Magnesium-L-threonate supplementation improved sleep quality, daytime functioning, and mood in adults with self-reported sleep problems 1.
  • The supplementation also increased deep sleep score, REM sleep score, and improved light sleep time, activity, and readiness parameters 1.
  • Magnesium works by regulating neurotransmitters that calm the nervous system and by binding to gamma-aminobutyric acid (GABA) receptors, which helps quiet nerve activity 1.

Recommendations

  • Consider taking 1g/day of Magnesium-L-threonate supplementation for 21 days to improve sleep quality and daytime functioning 1.
  • Start with a lower dose and increase gradually if needed, as high doses may cause digestive issues like diarrhea.
  • People with kidney disease should consult their doctor before taking magnesium supplements, as they may not be able to clear excess magnesium effectively.

Important Considerations

  • While other studies have shown mixed results, the most recent and highest quality study suggests that Magnesium-L-threonate supplementation can be an effective treatment for improving sleep quality 1.
  • Cognitive behavioral therapy (CBT) is also an effective treatment for insomnia, especially in patients with mental disorders and comorbid insomnia 2.
  • A systematic review of available literature found an association between magnesium status and sleep quality, but the evidence is limited by the quality of the studies 3.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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