What is the diagnosis for a person with Attention Deficit Hyperactivity Disorder (ADHD), restless legs syndrome, tachycardia, cervical and right hand inflammation, nocturnal low-grade fevers, pruritus, history of seizure, bloating, diarrhea, vomiting, abdominal pain, and motor weakness post-coitus?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Article Review Status
Submitted
Under Review
Approved

Last updated: April 2, 2025 • View editorial policy

Differential Diagnosis

The patient's complex presentation of symptoms requires a comprehensive differential diagnosis. The following categories outline potential diagnoses:

  • Single Most Likely Diagnosis + Lyme Disease: This diagnosis is considered due to the combination of symptoms such as irregular rapid heart rate, inflammation in the neck, and pruritus, which are common in Lyme disease. The presence of neurological symptoms like ADHD, restless legs, and a history of a seizure also supports this diagnosis, as Lyme disease can cause neurological manifestations. Additionally, gastrointestinal symptoms like bloating, diarrhea, vomiting, and abdominal pain can occur in Lyme disease.
  • Other Likely Diagnoses + Systemic Lupus Erythematosus (SLE): SLE is a possible diagnosis given the patient's symptoms of inflammation, fever, and pruritus. SLE can also cause neurological symptoms, gastrointestinal issues, and cardiac problems. + Rheumatoid Arthritis: This condition could explain the inflammation in the neck and right hand, as well as the systemic symptoms like fever and pruritus. + Multiple Sclerosis: The patient's neurological symptoms, such as motor weakness after sex, could be indicative of multiple sclerosis, especially if there are any visual or sensory symptoms present.
  • Do Not Miss Diagnoses + Neurosyphilis: This condition can cause a wide range of neurological symptoms, including ADHD-like symptoms, seizures, and motor weakness. It is essential to consider neurosyphilis due to its potential for severe consequences if left untreated. + Sarcoidosis: Sarcoidosis can cause inflammation in various parts of the body, including the lungs, skin, and nervous system, leading to a wide range of symptoms. + Vasculitis: Conditions like giant cell arteritis or polyarteritis nodosa can cause inflammation in blood vessels, leading to symptoms like fever, pruritus, and neurological issues.
  • Rare Diagnoses + Ehlers-Danlos Syndrome: This genetic disorder can cause a range of symptoms, including gastrointestinal issues, joint hypermobility, and neurological problems. + Mitochondrial Myopathies: These conditions can cause a variety of symptoms, including muscle weakness, gastrointestinal issues, and neurological problems. + Whipple's Disease: This rare bacterial infection can cause a range of symptoms, including gastrointestinal issues, fever, and neurological problems.

Each of these diagnoses requires careful consideration and further evaluation to determine the underlying cause of the patient's complex presentation of symptoms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.