Management of Perirectal Abscess
Primary Treatment: Surgical Drainage
Incision and drainage is the cornerstone of treatment for all perirectal abscesses and should be performed promptly once diagnosed. 1, 2 An undrained perirectal abscess can expand into adjacent spaces and progress to generalized systemic infection. 1
Timing of Surgical Intervention
The urgency of drainage depends on clinical presentation:
Emergency drainage (immediate) is required for patients with:
Urgent drainage (within 24 hours) for stable patients without the above risk factors 1, 2
Surgical Technique
The incision should be placed as close as possible to the anal verge to minimize potential fistula length while ensuring adequate drainage. 1, 2 This is critical because inadequate drainage is a major risk factor for recurrence. 1
Specific approach based on abscess location:
- Perianal and ischiorectal abscesses: drain via overlying skin 1, 2
- Intersphincteric abscesses: drain into the rectal lumen 1, 2
- Supralevator abscesses: drain via rectal lumen or externally through skin 2
For large abscesses, use multiple counter incisions rather than a single long incision to avoid step-off deformity and delayed wound healing. 1
Management of Concomitant Fistulas
During abscess drainage, if a fistula tract is identified:
- Perform primary fistulotomy ONLY for low fistulas not involving sphincter muscle 2
- Place a loose draining seton for any fistula involving sphincter muscle 2
This approach balances recurrence prevention (fistulotomy reduces recurrence from 44% to as low as 15% 1) against the risk of incontinence from sphincter damage.
Antibiotic Therapy
Antibiotics are NOT routinely indicated after adequate surgical drainage. 2, 3 However, antibiotics should be administered in specific circumstances:
Indications for Antibiotics
Add broad-spectrum antibiotics covering gram-positive, gram-negative, and anaerobic organisms when: 1
- Systemic signs of infection or sepsis are present 1, 2
- Patient is immunocompromised 1
- Source control is incomplete 1
- Significant surrounding cellulitis extends beyond abscess borders 1
Inadequate antibiotic coverage after drainage of complicated perirectal abscess results in a six-fold increase in readmission rates (28.6% vs 4%). 4 When antibiotics are indicated, ensure coverage matches the polymicrobial nature of these infections (mixed aerobic/anaerobic organisms in 37% of cases, mixed aerobic in 33%). 4
Outpatient vs Inpatient Management
Young, fit, immunocompetent patients with small perianal abscesses and no systemic signs of sepsis may be managed as outpatients. 1, 2 Small simple perianal abscesses can be treated under local anesthesia in an ambulatory setting. 1
Approximately 35% of patients require hospital admission, with risk factors including: 5
- Preoperative sepsis
- Bleeding disorders
- Non-Hispanic black or Hispanic race
- Morbid obesity
- Dependent functional status
Diagnostic Imaging
Clinical diagnosis based on history and physical examination is usually sufficient. 1, 2 The most common symptom is perirectal pain (present in 98.9% of cases), and external perianal plus digital rectal examination identifies the abscess in 94.6% of patients. 3
Consider imaging when:
- Atypical presentation 2
- Suspected supralevator or intersphincteric abscess 2
- Suspicion of Crohn's disease 2
- Do not delay drainage if imaging is unavailable when abscess is clinically suspected 2
When imaging is needed, CT scan offers advantages of short acquisition time and widespread availability, though MRI is the gold standard for perianal fistulizing Crohn's disease (76-100% accuracy). 2
Post-Operative Care and Follow-Up
- Routine imaging after incision and drainage is NOT required 1, 2
- Consider follow-up imaging only for: recurrence, suspected inflammatory bowel disease, evidence of fistula, or non-healing wound 1, 2
- Wound packing remains controversial and may be costly and painful without adding benefit 2
Common Pitfalls and Risk Factors for Recurrence
Recurrence rates can be as high as 44% after drainage alone. 1 Key risk factors include:
- Inadequate drainage (most important) 1, 2
- Loculations 1, 2
- Horseshoe-type abscess 1, 2
- Delayed time from disease onset to incision 1, 2
Complete and accurate drainage at the initial procedure is essential to prevent recurrence. 1 Needle aspiration has a 41% recurrence rate compared to 15% with proper incision and drainage. 1
Reoperations occur in 3.4% of cases (median 15.5 days later), with 79.7% performed for additional drainage, and readmissions occur in 3.0% (median 10.5 days later), most commonly for recurrent/persistent abscess (41.4%). 5