Is naproxen (Nonsteroidal Anti-Inflammatory Drug (NSAID)) available in 375mg tablets?

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Naproxen 375mg Tablet Availability

Yes, naproxen is available in 375mg tablets. 1

FDA-Approved Formulation

  • Naproxen tablets are manufactured and FDA-approved in three strengths: 250mg, 375mg, and 500mg for oral administration. 1

  • The 375mg tablet is specifically described as a white to off-white, oval-shaped tablet with "139" debossed on one side and plain on the other side. 1

  • This formulation is packaged in light-resistant bottles of 100 or 500 tablets (NDC 52605-139-01 for 100 tablets; NDC 52605-139-05 for 500 tablets). 1

Clinical Context

  • The 375mg strength provides an intermediate dosing option between the 250mg and 500mg tablets, allowing for flexible dosing strategies in pain management. 1

  • Naproxen has been established as an effective NSAID for various pain conditions, with a well-documented safety profile over many years of clinical use. 2, 3

  • The drug should be stored at 20°-25°C (68°-77°F) in well-closed, light-resistant containers and requires a prescription (Rx only). 1

References

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