Differentiating Vertigo from Pre-Syncope
The key distinction is that vertigo is an illusion of rotation or spinning caused by vestibular system dysfunction, while pre-syncope is a sensation of impending faint caused by cerebral hypoperfusion—differentiate them by asking the patient to describe their sensation: spinning/rotation indicates vertigo, whereas lightheadedness with impending loss of consciousness indicates pre-syncope. 1, 2
Primary Distinguishing Features
Symptom Quality
- Vertigo patients describe: A spinning sensation, either of themselves or their environment rotating, which is an illusion of movement due to vestibular system disorder 2
- Pre-syncope patients describe: Lightheadedness, feeling faint, sensation of impending loss of consciousness, "graying out," or "tunnel vision" without rotational quality 1, 3
- The traditional approach of categorizing dizziness by symptom type (vertigo vs. presyncope) has limitations, but the fundamental distinction between rotational and non-rotational symptoms remains clinically useful 4
Associated Symptoms
Pre-syncope typically presents with:
- Extreme lightheadedness and sensation of warmth 1, 3
- Nausea, sweating, and weakness 1, 3
- Visual changes including tunnel vision or blurring 1, 3
- Pallor and diaphoresis on examination 3
- Symptoms related to decreased cerebral perfusion (systolic BP dropping toward 60 mmHg) 3
Vertigo typically presents with:
- Nystagmus on examination (a key differentiating physical finding) 2, 5
- Nausea and vomiting (can occur in both, but more prominent in vertigo) 2
- Imbalance and difficulty walking 2
- Auditory symptoms if Meniere's disease (hearing loss, tinnitus) 2
Temporal Pattern Analysis
Duration and Triggers
- Single prolonged episode (hours to days): Suggests vestibular neuritis or cerebellar infarction if vertigo; suggests cardiac or neurologic cause if pre-syncope 2, 6
- Brief recurrent episodes (<1 minute): Benign paroxysmal positional vertigo (BPPV) if triggered by head position changes; cardiac arrhythmia or orthostatic hypotension if pre-syncope 2, 6
- Recurrent episodes (minutes to hours): Meniere's disease or vestibular migraine if vertigo; neurally mediated syncope if pre-syncope 2, 6
Positional Relationship
- Vertigo: Triggered by specific head movements or positions (especially BPPV) 2
- Pre-syncope: Triggered by standing (orthostatic hypotension), exertion, or prolonged standing (neurally mediated) 3, 6
Critical Physical Examination Maneuvers
For Suspected Vertigo
- Head impulse test: Distinguishes peripheral vestibular disorders from central causes (cerebellar stroke)—requires mastery of technique 2
- Dix-Hallpike maneuver: Diagnostic for BPPV, the most common cause of recurrent vertigo 2, 4
- Nystagmus examination: Presence and pattern help localize vestibular pathology 5
For Suspected Pre-Syncope
- Orthostatic vital signs: Measure blood pressure and heart rate supine and after 1-3 minutes standing to diagnose orthostatic hypotension 3, 6
- Cardiac examination: Assess for structural heart disease, murmurs, and arrhythmias 7, 6
- Neurologic examination: Rule out focal deficits that would suggest stroke or other neurologic process 7
High-Risk Features Requiring Urgent Evaluation
Pre-syncope Red Flags
- Age >60 years, male gender, known cardiac disease 3
- Occurrence during exertion or in supine position 3
- Palpitations preceding the episode 3
- Family history of sudden cardiac death 3
- Abnormal ECG findings 6
These features suggest cardiac syncope, which carries significantly increased mortality risk and requires immediate evaluation 3, 6
Vertigo Red Flags
- Acute isolated vertigo with inability to walk: May indicate cerebellar stroke rather than benign vestibular neuritis 2
- New focal neurologic signs: Suggest central (brainstem/cerebellar) rather than peripheral vestibular pathology 2, 5
- Severe headache with vertigo: Consider posterior circulation stroke 2
Common Diagnostic Pitfalls
- Do not rely solely on patient's use of the word "dizziness"—patients use this term loosely for both vertigo and pre-syncope; you must clarify whether they experience spinning vs. lightheadedness 8
- Do not assume brief episodes are benign—both BPPV (benign) and cardiac arrhythmias (dangerous) cause brief recurrent episodes 2, 6
- Do not order routine head CT for uncomplicated presentations—imaging has <1% yield for acute abnormalities in syncope/presyncope without head trauma or focal neurologic deficits 7
- Do not dismiss presyncope as less serious than syncope—both have similar short-term serious outcomes and mortality rates and should be evaluated identically 7, 1
Practical Diagnostic Algorithm
- Clarify the sensation: Spinning/rotation = vertigo pathway; lightheadedness/impending faint = pre-syncope pathway 1, 2
- Assess timing: Single prolonged vs. brief recurrent vs. episodic pattern 4
- Identify triggers: Positional (head movement vs. standing), exertional, or spontaneous 4
- Perform targeted examination: Nystagmus and Dix-Hallpike for vertigo; orthostatic vitals and cardiac exam for pre-syncope 2, 6
- Risk stratify: Apply high-risk features to determine need for urgent evaluation vs. outpatient management 3, 6