What is the dosage and administration of Ibuprofen (Nonsteroidal Anti-Inflammatory Drug, NSAID)?

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From the Guidelines

布洛芬的典型用法是每天口服或静脉注射600毫克一次或两次,对于严重的不良反应,可以考虑减少到每天300毫克一次。根据1的研究,布洛芬的用法和用量如下:

  • 成人和青少年:口服或静脉注射600毫克一次或两次
  • 儿童(1周至12岁):根据WHO的抗结核药物耐药性推荐:
  • 1周至9岁:每天10毫克/千克两次(最大600毫克/天)
  • 10岁以上:每天10毫克/千克一次(最大600毫克/天) 对于布洛芬的使用,需要注意以下几点:
  • 应该与食物或牛奶一起服用,以减少胃部刺激
  • 对于轻微的疼痛或发热,通常使用1-3天,而对于炎症性疾病,如关节炎,可能需要在医生的监督下长期使用
  • 布洛芬通过抑制前列腺素的产生来减少炎症、疼痛和发热
  • 不良反应可能包括胃部不适、心burn和长期使用增加心血管事件的风险
  • 如果您有肾脏疾病、心力衰竭、胃溃疡或处于怀孕的第三个月份,应避免使用布洛芬
  • 如果症状持续超过3天伴随发热或10天伴随疼痛,应咨询医疗保健提供者。

From the FDA Drug Label

DOSAGE AND ADMINISTRATION Carefully consider the potential benefits and risks of ibuprofen tablets and other treatment options before deciding to use ibuprofen tablets. Use the lowest effective dose for the shortest duration consistent with individual patient treatment goals [see WARNINGS] After observing the response to initial therapy with ibuprofen tablets, the dose and frequency should be adjusted to suit an individual patient's needs. Do not exceed 3200 mg total daily dose. If gastrointestinal complaints occur, administer ibuprofen tablets with meals or milk Rheumatoid arthritis and osteoarthritis, including flare-ups of chronic disease: Suggested Dosage: 1200 mg to 3200 mg daily (400 mg, 600 mg or 800 mg tid or qid). Mild to moderate pain: 400 mg every 4 to 6 hours as necessary for relief of pain. Dysmenorrhea: For the treatment of dysmenorrhea, beginning with the earliest onset of such pain, ibuprofen tablets should be given in a dose of 400 mg every 4 hours as necessary for the relief of pain.

布洛芬的用法用量如下:

  • 风湿性关节炎和骨关节炎:每日1200毫克至3200毫克(400毫克、600毫克或800毫克,三次或四次 denně)
  • 轻度至中度疼痛:每4至6小时400毫克,根据需要
  • 痛经:每4小时400毫克,根据需要 总日剂量不超过3200毫克 2

From the Research

布洛芬用法用量

  • 布洛芬是一种非甾体抗炎药(NSAID),常用于治疗类风湿关节炎、骨关节炎等疾病 3
  • 布洛芬的用法用量取决于具体的病况和患者的反应,通常按照医生的处方进行使用。
  • 研究表明,布洛芬在低剂量时对胃肠道的风险较低,但在高剂量或长期使用时可能会增加胃肠道并发症的风险 4
  • 布洛芬与其他NSAID(如萘普生、塞来昔布)相比,在某些情况下可能具有更好的安全性特征,特别是在心血管和胃肠道方面 5
  • 患有风湿关节炎或骨关节炎的患者在使用布洛芬时应注意其对骨折风险的潜在影响,尽管这种影响可能较小 6

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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