Does Vicryl (Polyglactin 910) suture cause adhesions?

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Last updated: April 2, 2025View editorial policy

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From the Research

V-Loc suture can potentially cause adhesions, though it's designed to minimize this risk compared to traditional sutures. The use of V-Loc sutures, like all foreign materials placed in the body, can trigger an inflammatory response that may lead to adhesion formation 1. The risk varies depending on placement location, with intraperitoneal use carrying higher concern.

Key Considerations

  • Surgeons often take precautions when using V-Loc in sensitive areas by burying the suture ends and avoiding leaving excess material.
  • The barbed design, while beneficial for tissue approximation, presents more surface area for tissue interaction than smooth sutures.
  • To minimize adhesion risk, V-Loc should be used according to manufacturer guidelines, with careful attention to proper tissue handling, minimal tension, and appropriate suture selection for the specific surgical application.
  • Proper irrigation and hemostasis during surgery also help reduce adhesion formation regardless of suture type used.

Evidence-Based Recommendations

  • A systematic review of barrier materials for preventing surgical adhesions found that various materials, including synthetic and natural barriers, can reduce adhesion formation 1.
  • Another study found that absorbable sutures, such as those used in V-Loc, can lead to a reduced risk of wound dehiscence compared to non-absorbable sutures 2.
  • However, the use of V-Loc sutures should be carefully considered, as they can still cause adhesions, especially in sensitive areas 3, 4, 5.

Best Practices

  • Use V-Loc sutures according to manufacturer guidelines.
  • Minimize tissue trauma and handle tissues with care.
  • Use proper irrigation and hemostasis during surgery.
  • Consider alternative suture materials or techniques in sensitive areas.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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