Treatment of Acute Bronchitis
Antibiotics should NOT be prescribed for uncomplicated acute bronchitis, regardless of cough duration or sputum color, as they provide minimal benefit (reducing cough by only half a day) while exposing patients to unnecessary adverse effects and contributing to antibiotic resistance. 1, 2, 3, 4
Initial Assessment: Rule Out Pneumonia First
Before diagnosing acute bronchitis, assess for pneumonia by checking for:
- Tachycardia (heart rate >100 beats/min) 3
- Tachypnea (respiratory rate >24 breaths/min) 3
- Fever (oral temperature >38°C) 3
- Abnormal chest examination findings (rales, egophony, tactile fremitus) 3
Chest radiography is NOT indicated in healthy, nonelderly adults without vital sign abnormalities or asymmetrical lung sounds. 1, 5
First-Line Symptomatic Treatment
Bronchodilators (Albuterol)
Albuterol (short-acting β-agonist) is the first-line symptomatic treatment for acute bronchitis, particularly in patients with wheezing or evidence of bronchial hyperresponsiveness. 2, 3
- Reduces both duration and severity of cough 2
- Approximately 50% fewer patients report cough after 7 days of treatment 2
- Should be offered to patients with wheezing accompanying the cough 3
Antitussives
For bothersome cough without wheezing:
- Dextromethorphan or codeine provide modest effects on cough severity and duration 1, 2, 3
- These agents are more effective for cough lasting >3 weeks compared to early viral upper respiratory infections 1
Low-Risk Adjunctive Measures
- Elimination of environmental cough triggers (dust, dander) 1, 2
- Vaporized air treatments, particularly in low-humidity environments 1, 2
When Antibiotics ARE Indicated
Exception #1: Pertussis (Whooping Cough)
If pertussis is suspected or confirmed:
- Prescribe a macrolide antibiotic (such as erythromycin) 3
- Isolate patients for 5 days from start of treatment 3
- Early treatment within first few weeks diminishes coughing paroxysms and prevents disease spread 3
Exception #2: High-Risk Patients
Consider antibiotics only in:
- Elderly patients 3
- Immunocompromised individuals 3
- Patients with comorbidities (COPD, heart failure) 3
- If condition significantly worsens, suggesting bacterial superinfection 3
What NOT to Do
Do NOT prescribe antibiotics based on:
- Purulent or colored sputum - this does NOT signify bacterial infection 3, 6, 4
- Duration of cough - antibiotics are not indicated regardless of how long the cough persists 1, 2
- Patient expectation - satisfaction depends on communication, not antibiotics 1
Do NOT routinely use:
- β2-agonist bronchodilators in patients without wheezing 3
- NSAIDs at anti-inflammatory doses 3
- Systemic corticosteroids 3
- Expectorants or mucolytics - lack evidence of benefit 5
Patient Education Strategy
Set realistic expectations:
- Inform patients that cough typically lasts 10-14 days after the office visit 2, 3
- Refer to the condition as a "chest cold" rather than bronchitis to reduce antibiotic expectations 3, 4
- Explain that patient satisfaction depends on physician-patient communication rather than antibiotic prescription 1
- Discuss risks of unnecessary antibiotic use, including side effects and antibiotic resistance 3
Common Pitfalls to Avoid
- Prescribing antibiotics for uncomplicated acute bronchitis despite clear evidence showing lack of benefit 2, 5
- Failing to distinguish between acute bronchitis and pneumonia - always assess vital signs and chest examination 5
- Not providing realistic expectations about illness duration, leading to unnecessary follow-up visits or antibiotic requests 2
- Overlooking bronchodilator therapy in patients with wheezing, which has demonstrated benefit 2, 5
- Confusing acute bronchitis with acute exacerbations of chronic bronchitis - the latter may require antibiotics in specific circumstances 5, 7, 8