Initial Evaluation and Management of Knee Pain
Begin with plain radiographs of the knee (minimum two views: anteroposterior and lateral) for all patients ≥5 years old presenting with knee pain, whether acute or chronic. 1, 2
History: Key Elements to Document
Age and onset pattern: Patients <40 years with anterior knee pain during squatting suggest patellofemoral pain (91% sensitive), while patients ≥45 years with activity-related pain and <30 minutes of morning stiffness suggest osteoarthritis (95% sensitive) 3
Mechanical symptoms: Document locking, catching, or giving way, which may indicate meniscal pathology (joint line tenderness 83% sensitive and specific; McMurray test 61% sensitive, 84% specific) 3
Red flags requiring urgent evaluation: Fever with joint swelling/erythema (septic arthritis), gross deformity, palpable mass, penetrating injury, inability to bear weight with severe pain/swelling after trauma 1, 2, 4
Weight-bearing ability and range of motion: Critical for applying Ottawa Knee Rules in acute trauma 1, 2
Physical Examination: Systematic Approach
Inspection: Assess for effusion, erythema, deformity, and muscle atrophy 4
Palpation: Check for focal tenderness over fibular head, isolated patellar tenderness, joint line tenderness, and warmth 1, 2
Range of motion testing: Document ability to flex knee to 90° (Ottawa criteria) and presence of crepitus 1, 4
Provocative maneuvers: Perform McMurray test for meniscal tears, patellar apprehension test for instability, and assess for ligamentous laxity 4, 3
Neurovascular examination: Essential to exclude referred pain from hip or spine pathology 4
Imaging Algorithm
For Acute Trauma (Use Ottawa Knee Rules)
Order radiographs if ANY of the following criteria are met: 1, 2
- Age ≥55 years
- Isolated patellar tenderness
- Fibular head tenderness
- Inability to flex knee to 90°
- Inability to bear weight immediately after injury or take 4 steps in emergency department
Additional views beyond standard AP/lateral: Consider cross-table lateral, patellofemoral (sunrise), and oblique views for comprehensive evaluation 2
For Chronic Knee Pain (>6 weeks)
Initial radiographs should include: Frontal projection, tangential patellar view, and lateral view 1, 2
If radiographs are normal or show only effusion: MRI without contrast is usually appropriate as the next step to evaluate soft tissue structures, menisci, ligaments, and bone marrow lesions 1, 2
If radiographs show degenerative changes: MRI may be appropriate only when symptoms are not explained by radiographic findings or when stress fractures are suspected 1
Consider hip or lumbar spine radiographs: If knee radiographs are unremarkable and referred pain is suspected 2
Common Pitfalls to Avoid
Do not order MRI without recent radiographs first: This occurs inappropriately in ~20% of chronic knee pain cases 2
Recognize incidental findings: Meniscal tears are frequently present in asymptomatic older patients and may not be the pain source 2, 3
Avoid unnecessary imaging in acute trauma: Applying Ottawa rules can reduce radiographs by 23-35% while maintaining 100% sensitivity for fractures 1
When to Consider Advanced Imaging
CT without contrast: Appropriate when radiographically occult fractures are suspected (100% sensitive for tibial plateau fractures vs 83% for radiographs) or for detailed patellofemoral anatomy evaluation 1, 2
Ultrasound: Useful for confirming effusions, guiding aspiration, detecting Baker cysts, and evaluating superficial structures, but not as a comprehensive screening tool 1, 2
Joint aspiration: Indicated when infection or crystal disease is suspected, can be ultrasound or fluoroscopy-guided 1
Initial Management Based on Diagnosis
Osteoarthritis (Most Common in ≥45 Years)
- First-line treatment: Exercise therapy, weight loss if overweight, education, and self-management programs 3
- Avoid: Routine MRI in typical OA cases unless symptoms unexplained by radiographs 1
Patellofemoral Pain (Common in <40 Years, Active Patients)
- First-line treatment: Hip and knee strengthening exercises combined with foot orthoses or patellar taping 3
- No indication for surgery 3
Meniscal Tears
- Conservative management first: Exercise therapy for 4-6 weeks, even with mechanical symptoms in degenerative tears 3
- Surgery only for: Severe traumatic bucket-handle tears with displaced tissue 3
Urgent Referral Criteria
Immediate orthopedic consultation required for: 2, 4
- Suspected septic arthritis (fever, severe swelling, erythema, limited ROM)
- Severe pain with instability and inability to bear weight after acute trauma
- Gross deformity or neurovascular compromise
- Locked knee that cannot be extended