What is the recommended treatment for pulmonary vein injury due to trauma?

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Last updated: November 26, 2025View editorial policy

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Repair of Pulmonary Vein Injury in Trauma

Pulmonary vein injuries from trauma require immediate surgical repair via thoracotomy with direct suturing under cardiopulmonary bypass support, as these injuries are life-threatening and cannot be managed conservatively. 1, 2, 3

Immediate Recognition and Resuscitation

  • Suspect pulmonary vein injury in blunt or penetrating chest trauma patients presenting with hemopericardium, cardiac tamponade, or hemodynamic instability despite initial resuscitation. 1, 2, 3

  • Transthoracic echocardiography is essential to identify pericardial effusion and guide the decision for emergency surgery. 1, 2

  • Patients with identified bleeding sources and hemodynamic instability require immediate surgical bleeding control rather than prolonged resuscitation attempts. 4

  • During initial resuscitation, maintain normoventilation (PaCO2 5.0-5.5 kPa) and avoid hyperventilation, which worsens outcomes in trauma patients through decreased cerebral perfusion and cardiovascular collapse. 4

Surgical Approach and Technique

  • Establish cardiopulmonary bypass before attempting definitive repair, as this provides hemodynamic stability and optimal visualization of all injuries. 1, 3

  • The medial approach to thoracotomy allows adequate exposure for inspection and repair of pulmonary vein injuries. 1

  • Direct repair using 4-0 or 5-0 polypropylene running sutures is the standard technique for pulmonary vein lacerations. 1, 2

  • Catastrophic hemorrhage commonly occurs when releasing pericardial clot; cardiopulmonary bypass must be established before complete evacuation to prevent exsanguination. 1

  • Carefully inspect for concomitant injuries including cardiac chamber ruptures, inferior vena cava lacerations, and pericardial tears, as these frequently occur together. 1, 2

Postoperative Management

  • Initiate lung-protective ventilation with low tidal volumes (<6 mL/kg predicted body weight) and moderate PEEP immediately postoperatively to prevent acute lung injury. 4, 5

  • Begin mechanical thromboprophylaxis immediately in all patients without absolute contraindications. 4

  • Start LMWH-based pharmacologic thromboprophylaxis within 48-72 hours of injury once hemostasis is secured, as delays beyond 72 hours increase VTE risk over fourfold. 4

  • For patients with massive pulmonary vein trauma causing treatment-refractory hypoxemia, inhaled nitric oxide may reverse hypoxemia when conventional ventilation fails. 6

  • Early enteral feeding should begin within 72 hours when hemodynamically stable and not requiring vasopressor support. 4

Critical Pitfalls to Avoid

  • Never attempt repair without cardiopulmonary bypass capability, as uncontrolled hemorrhage during repair is uniformly fatal. 1, 3

  • Do not delay surgical intervention for additional imaging once hemopericardium with hemodynamic instability is identified—this represents a surgical emergency. 1, 2

  • Avoid hyperventilation during resuscitation, as PaCO2 <27 mmHg causes neuronal injury, cerebral vasoconstriction, and impaired venous return leading to cardiovascular collapse. 4

  • Do not use high tidal volumes (>6 mL/kg), as even short-term ventilation with 12 mL/kg promotes pulmonary inflammation and coagulation abnormalities. 4

Prognosis

  • Survival is possible with prompt recognition and surgical repair under cardiopulmonary bypass, with patients achieving ambulatory discharge within 2-3 weeks. 1, 2

  • Isolated pulmonary vein ruptures are extremely rare; most cases involve multiple cardiac and great vessel injuries requiring comprehensive repair. 1, 2, 3

References

Research

Blunt chest trauma: a right pulmonary vein rupture.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2001

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Patient Self-Inflicted Lung Injury (P-SILI): Diagnosis and Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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