Management of Second Pregnancy After One Second Trimester Loss
Serial ultrasound monitoring of cervical length starting at 16-18 weeks is the recommended approach, with ultrasound-indicated cerclage placement only if cervical shortening is detected (cervical length <25mm). 1
Rationale Against Prophylactic Cerclage at 13 Weeks
A single second trimester loss does NOT meet criteria for history-indicated cerclage. The Society for Maternal-Fetal Medicine and major guidelines reserve history-indicated cerclage for women with three or more prior second trimester losses or preterm births due to painless cervical dilation, or classic features of cervical insufficiency. 1, 2
- History-indicated cerclage should be reserved for individuals with classic historical features of cervical insufficiency or an unexplained second-trimester loss in the absence of placental abruption. 1
- Prophylactic cerclage at 13 weeks in this patient would be premature and not evidence-based, as one loss alone does not establish cervical insufficiency. 2, 3
- Cerclage placement after previable PPROM was associated with increased odds of preterm birth (63.2% vs 10.9%; OR 14.0) in subsequent pregnancies, highlighting the importance of proper patient selection. 1
Recommended Surveillance Strategy
Serial transvaginal ultrasound (TVUS) cervical length screening is the evidence-based approach for this patient:
- Begin TVUS screening at 16-18 weeks gestation and continue every 1-2 weeks until 24 weeks. 1
- Cervical length <25mm is the threshold for intervention consideration. 1
- TVUS is highly reproducible and identifies changes at the internal os where preterm birth risk first manifests. 1
Intervention Based on Ultrasound Findings
If cervical shortening is detected (<25mm):
- Ultrasound-indicated cerclage reduces preterm birth by 30% before 35 weeks in high-risk patients with short cervical length. 1
- Alternative interventions include vaginal progesterone (44% reduction in PTB <34 weeks) or cervical pessary (78% reduction in PTB <34 weeks). 1
- The decision between cerclage, progesterone, or pessary should incorporate the specific cervical length measurement, presence of funneling, and patient history. 1
Why Clinical Assessment Alone is Insufficient
Digital cervical examination is not recommended as the primary screening method because:
- TVUS is superior to digital examination for detecting early cervical changes. 1
- By the time cervical dilation is clinically apparent, the window for effective intervention may have passed. 1
- TVUS provides objective, reproducible measurements that guide evidence-based interventions. 1
Critical Timing Considerations
- Do not place cerclage at 18 weeks routinely without documented cervical shortening, as this represents therapeutic/urgent cerclage timing but requires ultrasound evidence of cervical insufficiency. 4
- Cerclage placement between 13-16 weeks is reserved for history-indicated cases (≥3 prior losses), which this patient does not meet. 4, 2
- If cervical shortening is detected on surveillance ultrasound, cerclage can be placed as ultrasound-indicated (therapeutic) cerclage at that time. 1, 2
Additional Management Recommendations
Follow guidelines for management of pregnant persons with previous spontaneous preterm birth: