What is the most likely diagnosis for a 7-month-old infant presenting with low-grade fever, dry cough, wheezing over both lung fields, tachycardia, tachypnea, and hyperinflation on chest X-ray?

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Last updated: November 27, 2025View editorial policy

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Diagnosis: Bronchiolitis

The most likely diagnosis is D. Bronchiolitis 1. This 7-month-old infant presents with the classic clinical constellation of viral bronchiolitis: low-grade fever, dry cough, bilateral wheezing, tachypnea (RR 47/min), and hyperinflation on chest X-ray in a child under 2 years of age 1, 2.

Clinical Reasoning

Bronchiolitis should be diagnosed based on history and physical examination alone 1. This infant demonstrates the pathognomonic features:

  • Age 1-12 months: Peak age for bronchiolitis, which specifically affects children from 1 month through 23 months 2
  • Viral prodrome: 3-day history of low-grade fever and cough consistent with upper respiratory infection preceding lower respiratory symptoms 3, 4
  • Lower respiratory signs: Bilateral wheezing indicating small airway involvement 1
  • Tachypnea: RR 47/min indicates increased work of breathing, a hallmark of bronchiolitis in infants 1-12 months 2
  • Radiographic findings: Hyperinflation with infiltrates is characteristic of bronchiolitis, reflecting air trapping from small airway obstruction and inflammation 1

Why Not the Other Options

Asthma (Option A) is unlikely because:

  • Asthma is extremely rare as a first presentation at 7 months of age 1
  • The acute febrile illness with 3-day prodrome points to infectious etiology 1
  • Asthma medications should not be used unless there is evidence of recurrent wheeze and/or dyspnea 1

Sinusitis (Option B) is incorrect because:

  • This infant has clear lower respiratory tract involvement with bilateral wheezing and tachypnea 1
  • Sinusitis does not cause hyperinflation on chest X-ray or bilateral wheezing 1

Influenza (Option C) is less likely because:

  • While influenza can cause bronchiolitis, it represents only one of multiple viral etiologies 1, 5
  • The clinical presentation is indistinguishable from RSV or other viral causes of bronchiolitis 1, 5
  • The diagnosis is bronchiolitis regardless of the specific viral etiology 1
  • Routine viral testing is not recommended as it does not change management 3, 4

Key Diagnostic Features of Bronchiolitis

Clinical criteria that confirm this diagnosis 1:

  • Acute inflammation of small airways in a child under 2 years 1, 2
  • Tachypnea, wheezing, and/or crackles following upper respiratory prodrome 1, 5
  • Increased respiratory effort (this infant has tachypnea at 47/min) 2

Important Clinical Pitfalls

Do not routinely order chest X-rays for bronchiolitis 1. Radiography should be reserved for:

  • Consideration of intubation 1
  • Unexpected clinical deterioration 1
  • Underlying cardiac or pulmonary disorder 1

This infant's chest X-ray was likely unnecessary unless there were concerns about severe disease or alternative diagnoses 1.

Risk stratification is essential: At 7 months, assess for risk factors including prematurity, chronic lung disease, congenital heart disease, or immunodeficiency, which would indicate higher risk for severe disease 1, 2.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Bronchiolitis in Young Children

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Respiratory Syncytial Virus Bronchiolitis in Children.

American family physician, 2017

Guideline

Respiratory Syncytial Virus Infection in Infants and Young Children

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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