Management of Subchorionic Hematoma on Obstetric Ultrasound
For small first-trimester subchorionic hematomas with documented fetal cardiac activity, expectant management with serial ultrasound monitoring is appropriate, while large hematomas or those in the second/third trimester require closer surveillance including umbilical artery Doppler studies and antenatal testing. 1, 2
Initial Diagnostic Assessment
When a subchorionic hematoma (SCH) is identified on ultrasound, document the following key features:
- Location relative to the placenta using transvaginal ultrasound as the primary imaging modality 1
- Presence of fetal cardiac activity using M-mode ultrasound or video clips (avoid pulsed Doppler in first trimester due to potential bioeffects on the developing embryo) 1
- Size of the hematoma both in absolute measurements and relative to gestational sac size 3
- Obtain quantitative beta-hCG level and complete blood count to assess for anemia and trend hormone levels 1
- Blood type and screen if not already on file, particularly to identify Rh-negative patients 1
First Trimester Management
Small Hematomas with Positive Cardiac Activity
- Prognosis is favorable when fetal cardiac activity is present 1
- Serial ultrasound examinations at 7-day intervals until bleeding ceases, hematoma disappears, or pregnancy outcome is determined 4, 5
- Consider bed rest during the duration of vaginal bleeding, as retrospective data suggests fewer spontaneous abortions (9.9% vs 23.3%) and higher term pregnancy rates (89% vs 70%) in women who adhered to bed rest compared to those who continued usual activities 5
Rh-Negative Patients
- Administer anti-D immunoglobulin (50 μg) to all Rh-negative patients with vaginal bleeding to prevent alloimmunization 1
Second and Third Trimester Management
SCH in later pregnancy carries higher risk and requires more intensive monitoring:
- Umbilical artery Doppler studies should be performed as part of comprehensive monitoring 4, 2
- Serial growth ultrasounds to monitor for fetal growth restriction, which is associated with second/third trimester SCH 2
- Antenatal fetal testing should be considered, particularly if the SCH is large or requires maternal blood transfusion 2
- Monitor for signs of hemodynamic instability in large SCH requiring hospitalization, with consideration of blood transfusion if significant blood loss occurs 4
Special Population: Anticoagulated Patients
If SCH is detected in a woman on anticoagulation:
- Immediately discontinue DOACs and switch to low molecular weight heparin 4
- Early obstetric review and enhanced fetal monitoring including assessment for subchorionic/retroplacental bleeding 6, 4
- Detailed first trimester scan (11-13+6 weeks) and anomaly scan (18-23 weeks) performed by experienced sonologist 6
- For DOAC exposure beyond first trimester, additional ultrasounds to monitor for fetal growth, well-being, and intracranial bleeding 6
Prognostic Factors
Poor prognostic indicators include:
- Large hematoma size (both relative and absolute) correlates with unfavorable outcomes 3
- Severity of vaginal bleeding is associated with worse prognosis 3
- Increasing hematoma size on follow-up examination predicts poor outcome 3
- Presence of maternal pain correlates with adverse outcomes 3
Common Pitfalls to Avoid
- Do not use pulsed Doppler ultrasound in first trimester for cardiac activity assessment; use M-mode instead to avoid potential bioeffects 1
- Do not confuse early first trimester SCH with normal decidual bleeding or other placental abnormalities like subamniotic hematomas 1
- Do not assume SCH is benign in second/third trimester—these cases are associated with preterm birth, preterm prelabor rupture of membranes, fetal growth restriction, and fetal demise 2
- Do not overlook Rh status—failure to administer anti-D immunoglobulin can lead to alloimmunization 1