What is the indication for Bentyl (Dicyclomine)?

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Last updated: April 2, 2025 • View editorial policy

From the Guidelines

Bentyl (dicyclomine) is primarily used to treat irritable bowel syndrome (IBS) and other digestive tract problems by relieving painful stomach and intestinal cramps. It belongs to a class of drugs called anticholinergics that work by blocking the action of acetylcholine, a chemical that causes muscle contractions in the digestive system 1. The typical adult dosage ranges from 20-40 mg taken 3-4 times daily, though treatment should always follow a doctor's prescription. Bentyl helps reduce abdominal pain, bloating, and irregular bowel movements by relaxing the smooth muscles in the gut. Some key points to consider when using Bentyl include:

  • Side effects may include dry mouth, blurred vision, dizziness, and constipation 2.
  • This medication is not recommended for certain individuals, including those with glaucoma, urinary retention, severe ulcerative colitis, or myasthenia gravis.
  • Patients should take Bentyl 30-60 minutes before meals for optimal effectiveness and should avoid alcohol while using this medication as it can increase drowsiness.
  • Antimuscarinics, such as dicycloverine, can be used for gastrointestinal smooth muscle spasm and may have a direct action on smooth muscle 3, 2. It's essential to weigh the benefits and risks of using Bentyl, considering the potential for side effects and interactions with other medications, and to consult a healthcare professional for personalized advice 4.

From the FDA Drug Label

Dicyclomine hydrochloride tablets, USP are indicated for the treatment of patients with functional bowel/irritable bowel syndrome.

Bentyl, also known as dicyclomine, is used for the treatment of functional bowel/irritable bowel syndrome 5.

From the Research

Bentyl Uses

  • Bentyl, also known as dicyclomine, is an antispasmodic agent used to treat symptoms of abdominal pain [ 6 ].
  • It is often prescribed for functional GI disorders, including irritable bowel syndrome, functional dyspepsia, and centrally mediated abdominal pain syndrome [ 6 ].
  • The medication works by inhibiting GI smooth muscle contraction, which helps to relieve abdominal pain and discomfort [ 6 ].
  • As an anticholinergic/antimuscarinic agent, Bentyl is part of a broader range of therapeutic classes with different mechanisms of action, including calcium channel inhibitors and direct smooth muscle relaxants [ 6 ].

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.