What should I do for a fever, dry cough, and sore throat?

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Management of Fever (38°C), Dry Cough, and Sore Throat

This presentation is most consistent with a viral upper respiratory tract infection that requires symptomatic treatment only—antibiotics are not indicated unless specific criteria for bacterial pharyngitis are met. 1, 2, 3

Immediate Assessment: Rule Out Bacterial Pharyngitis

The presence of cough actually argues against bacterial pharyngitis and strongly suggests a viral etiology. 1 Apply the modified Centor criteria to determine if testing for Group A Streptococcus is warranted: 1

  • Fever by history
  • Tonsillar exudates
  • Tender anterior cervical adenopathy
  • Absence of cough (your patient has cough, which counts against bacterial infection)

If fewer than 3 Centor criteria are met, do not test and do not prescribe antibiotics. 1 Since your patient has a dry cough, this alone significantly reduces the likelihood of streptococcal pharyngitis and makes viral infection far more probable. 1, 3

Recommended Management: Symptomatic Treatment

Provide symptomatic relief regardless of the underlying cause: 1, 2

  • Antipyretics for fever control: Ibuprofen or acetaminophen (paracetamol) 2, 4
  • Analgesics for throat pain 1, 3
  • Throat lozenges 1
  • First-generation antihistamines 1
  • Decongestants 1
  • Adequate fluid intake to maintain hydration 2
  • Rest to reduce metabolic demands 2

Avoid cough suppressants like dextromethorphan in the absence of clear indication, as efficacy is unproven and risks exist. 2, 5

Expected Clinical Course and Safety-Netting

Reassure the patient that typical sore throat resolves in less than 1 week, and acute bronchitis is self-limited. 1 Fever typically settles in 2-4 days, though cough may persist 1-2 weeks. 2

Monitor for red flags that require immediate re-evaluation: 2, 3

  • Fever persisting >4-5 days without improvement 2, 3
  • Development of respiratory distress (tachypnea, retractions, hypoxia) 2, 3
  • Altered consciousness or drowsiness 2
  • Severe dehydration or inability to take oral fluids 2
  • Cyanosis 2

When to Consider Antibiotics

Only prescribe antibiotics if Group A Streptococcus is confirmed by rapid antigen detection test or throat culture. 1 If testing is positive, use penicillin (oral for 10 days) or amoxicillin as first-line treatment. 1 For penicillin allergy, use first-generation cephalosporins or macrolides. 1

If pneumonia is suspected based on abnormal lung auscultation, respiratory distress, or persistent high fever, obtain a chest X-ray before initiating antibiotics. 3 If pneumonia is confirmed, prescribe a minimum of 5 days of antibiotics. 1

Common Pitfalls to Avoid

  • Do not prescribe antibiotics for viral bronchitis—they cause more harm than benefit and contribute to antibiotic resistance. 3
  • Do not rely on fever duration alone to diagnose bacterial infection; 5 days of fever warrants evaluation but does not automatically indicate bacterial etiology. 3
  • Do not use antibiotics prophylactically to prevent complications in low-risk patients. 2
  • Never use aspirin in children under 16 years due to Reye syndrome risk. 2

References

Guideline

Antibiotic Use in Patients with Cough and Purulent Phlegm

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Viral Upper Respiratory Infection Diagnosis and Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Clinical Assessment and Management of Dry Cough with Fever

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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