Acute Left-Sided Diverticulitis with Systemic Inflammatory Response
This patient most likely has acute left-sided colonic diverticulitis (ALCD) and requires immediate CT abdomen/pelvis with IV contrast for diagnosis, followed by broad-spectrum antibiotics and surgical consultation if complicated disease is identified. 1
Clinical Presentation Analysis
The constellation of findings strongly suggests ALCD rather than appendicitis despite the positive Rovsing's sign:
- Left lower quadrant pain and tenderness is the hallmark of ALCD, with pain typically localized to the left side 1
- Fever (38.9°C), tachycardia (120), and tachypnea (30) indicate systemic inflammatory response syndrome (SIRS), suggesting complicated diverticulitis with possible abscess or perforation 1
- Positive Rovsing's sign on the left (left-sided pain with right abdomen palpation) is an atypical finding that can occur with left-sided pathology when peritoneal irritation is present 2
- Irregular bowel movements (3x/week) and constipation are risk factors for diverticulitis 1
- Age 59 places this patient in the typical demographic for ALCD, with prevalence of 32.6% for diverticulosis in ages 50-59 1
Immediate Diagnostic Workup
CT abdomen/pelvis with IV contrast is the gold standard and must be obtained urgently:
- CT has 90% sensitivity and 90% specificity for diagnosing ALCD 1
- IV contrast is essential to characterize bowel wall abnormalities, detect abscesses, and identify complications 1
- CT will differentiate uncomplicated from complicated diverticulitis and guide management decisions 1
Ultrasound can be considered as initial imaging if CT is not immediately available, with 90% sensitivity and 90% specificity, though CT remains superior 1
Initial Management Algorithm
Immediate Stabilization 1
- NPO status (nothing by mouth)
- IV access and fluid resuscitation to address tachycardia and potential sepsis
- Vital sign monitoring given SIRS criteria (fever, tachycardia, tachypnea)
- Laboratory tests: CBC, CRP, lactate, comprehensive metabolic panel 1
Risk Stratification 1
This patient meets SIRS criteria (temperature >38°C, heart rate >90, respiratory rate >20), requiring assessment for sepsis:
- Check serum lactate immediately
- If lactate >2 mmol/L with hypotension requiring vasopressors, this constitutes septic shock 1
Treatment Based on CT Findings
Uncomplicated Diverticulitis (No Abscess/Perforation)
- Antibiotics are NOT routinely recommended for uncomplicated diverticulitis without systemic inflammation 1
- However, given this patient's fever and SIRS, antibiotics are indicated 1
- Oral antibiotics preferred when feasible to facilitate shorter hospital stay 1
- Broad-spectrum coverage for gram-negative and anaerobic organisms
Complicated Diverticulitis
Small abscess (<4 cm): Antibiotics alone may suffice 1
Larger abscess: CT-guided percutaneous drainage plus antibiotics 1
Diffuse peritonitis or free perforation:
- Urgent surgical consultation required 1
- Hartmann's procedure remains the standard for critically ill patients with diffuse peritonitis 1
- Damage control approach for physiologically deranged patients 1
Critical Pitfalls to Avoid
Do not dismiss left-sided pathology based on positive Rovsing's sign alone - this sign can be present with any peritoneal irritation and does not exclusively indicate appendicitis 2
Do not delay imaging in a patient with SIRS - the combination of fever, tachycardia, and tachypnea with abdominal pain requires urgent CT to identify source control needs 1
Do not use plain radiographs as primary diagnostic tool - they have only 49% sensitivity for detecting inflammatory processes 3
Consider alternative diagnoses if CT is negative for diverticulitis:
- Epiploic appendagitis (focal left-sided pain, normal WBC, no fever - less likely here given fever) 4
- Colonic malignancy with perforation
- Inflammatory bowel disease with abscess 1
Antibiotic Selection
Empiric broad-spectrum antibiotics should cover:
- Gram-negative organisms (E. coli, Klebsiella)
- Anaerobes (Bacteroides fragilis)
Common regimens include fluoroquinolone plus metronidazole, or beta-lactam/beta-lactamase inhibitor combinations 1