Healthcare Maintenance for Asymptomatic Adults
For asymptomatic adults, healthcare maintenance should focus on age-appropriate screening, risk factor assessment, and preventive interventions rather than routine comprehensive testing, with specific recommendations varying by age, sex, and individual risk factors. 1
Age-Based Screening Recommendations
Cardiovascular Risk Assessment
- Screen all adults aged 35 years and older for diabetes using HbA1c, fasting plasma glucose, or 2-hour OGTT every 3 years if initial results are normal 1
- Obtain fasting lipid profiles (total cholesterol, LDL, HDL, triglycerides) to assess cardiovascular risk, with repeat testing every 6-12 months in patients with identified risk factors 1
- Measure blood pressure annually using proper technique to avoid over-diagnosis and over-treatment 1
- In asymptomatic patients with diabetes, routine screening for coronary artery disease is not recommended as it does not improve outcomes when atherosclerotic cardiovascular disease risk factors are treated 2
Cancer Screening
- Breast cancer screening is recommended for women 40 years and older with life expectancy greater than 5 years 3
- Colorectal cancer screening is recommended for adults 50 years and older with life expectancy greater than 5 years 3
- Abdominal aortic aneurysm screening is recommended for men 65 to 75 years of age 3
Eye Examinations
The recommended frequency for comprehensive eye examinations in asymptomatic adults without risk factors is 2:
- Under 40 years: every 5 to 10 years
- 40 to 54 years: every 2 to 4 years
- 55 to 64 years: every 1 to 3 years
- 65 years or older: every 1 to 2 years
Increased frequency is recommended for adults with risk factors for glaucoma, such as African Americans and Hispanics 2
Diabetes-Specific Eye Screening
For patients with diabetes 2:
- Type 1 diabetes: first examination 5 years after onset, then yearly
- Type 2 diabetes: first examination at diagnosis, then yearly
- Pregnant women with diabetes: examination prior to conception and early in first trimester
Laboratory Testing
Core Laboratory Panel
- Complete blood count (CBC) for baseline hematologic assessment 1
- Comprehensive metabolic panel including electrolytes, creatinine with eGFR, and liver function tests (ALT, AST, total bilirubin, alkaline phosphatase) 1
- Thyroid-stimulating hormone (TSH) particularly if symptoms suggest thyroid dysfunction 1
- Urinalysis to screen for proteinuria, hematuria, or other renal abnormalities 1
Risk-Based Testing
- Sexually transmitted disease screening (syphilis, gonorrhea, chlamydia) if multiple sexual partners or new partners, with annual testing for those at risk 1
- Hepatitis B and C screening based on risk factors including injection drug use, multiple sexual partners, or occupational exposure 1
- Enhanced metabolic screening including waist circumference if BMI ≥25 kg/m² 1
Screening NOT Recommended
Respiratory Conditions
- Do not screen for COPD in asymptomatic adults, as early detection before symptom development does not alter disease course or improve outcomes 2
- The USPSTF determined with moderate certainty that screening for COPD in asymptomatic persons has no net benefit 2
Sleep Disorders
- Insufficient evidence exists to recommend for or against screening for obstructive sleep apnea in asymptomatic adults 2
- Evidence on screening tools to accurately detect persons who should receive further testing is lacking 2
Preventive Interventions
Lifestyle Counseling
- Counsel on smoking cessation, diets rich in healthy fats, aerobic exercise, and strength training 3
- Physical inactivity, poor diet, and tobacco use are actual causes of death that are modifiable through behavior change 3
Vaccinations
- Tetanus and diphtheria, pneumococcal, and influenza vaccines are recommended for patients 65 years and older 3
- Annual influenza vaccination is recommended for patients with established cardiovascular disease 2
Aspirin Therapy
- Consider aspirin therapy based on cardiovascular risk assessment 3
Critical Pitfalls to Avoid
- Do not use improper blood pressure measurement technique, which leads to over-diagnosis and over-treatment of hypertension 1
- Do not order non-fasting lipid panels when fasting values are required for accurate cardiovascular risk assessment 1
- Do not use point-of-care HbA1c devices for diagnosis without quality assurance participation; only laboratory-based NGSP-certified methods should be used 1
- Do not overlook family history assessment, which significantly impacts screening recommendations for diabetes, cardiovascular disease, and cancer 1
- Do not initiate treatment for asymptomatic hypertension in the emergency department when follow-up is available, as rapidly lowering blood pressure is unnecessary and may be harmful 2
- Do not screen for isolated asymptomatic hyperamylasemia as no acute treatment is indicated and it should not be misdiagnosed as acute pancreatitis 4