Meril Life Sciences Aortic Valve Material Composition
I cannot provide specific information about Meril Life Sciences aortic valve materials from the evidence provided, as none of the guideline or research documents contain information about this manufacturer's products.
What the Evidence Does Cover
The available guidelines and research exclusively discuss other manufacturers' valve materials:
Transcatheter Aortic Valves (TAVR)
- Edwards SAPIEN valves utilize bovine pericardium leaflets mounted on either stainless steel (original) or cobalt-chromium alloy frames (SAPIEN XT), as documented by the American College of Cardiology 1
- Medtronic CoreValve uses porcine pericardial tissue leaflets mounted in a self-expanding nitinol (nickel-titanium) frame 1, 2
Surgical Bioprosthetic Valves
- Stented porcine valves consist of intact porcine aortic valve cusps or tricomposite constructions using cusps from three different pigs (examples: Medtronic Mosaic, St Jude Epic) 1
- Stented pericardial bioprostheses use bovine pericardium (occasionally porcine) cut and sewn to stent posts (examples: Mitroflow, Trifecta) 1
- Stentless valves typically use porcine aorta preparations or bovine pericardium (examples: Medtronic Freestyle, Sorin Freedom) 1
Material Properties from Research
- Bovine pericardium demonstrates superior collagen content (7.98 vs 4.56 μg/mg dry weight) compared to porcine valve tissue, suggesting better structural integrity for prosthetic valve manufacturing 3
- All bioprosthetic tissues undergo glutaraldehyde fixation, which masks antigenic epitopes and eliminates the need for immunosuppression 4, 5
To obtain accurate information about Meril Life Sciences aortic valve composition, you must consult the manufacturer's product specifications, instructions for use (IFU), or contact the company directly, as this information is not available in standard cardiovascular imaging or TAVR guidelines.