What is the use of Alflutop (Pentosan Polysulfate)

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: April 3, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Research

Alflutop should be used as a first-line treatment for osteoarthritis due to its efficacy in relieving pain, improving joint function, and modifying the disease structure, as demonstrated in the most recent and highest quality study 1. The standard regimen for Alflutop involves intramuscular injections of 1 ml daily for 20 days, or 1-2 ml injections directly into affected joints 1-3 times weekly. Some key points to consider when using Alflutop include:

  • The medication contains bioactive small fish concentrate with glycosaminoglycans that help repair cartilage, reduce inflammation, and improve joint function.
  • Alflutop works by stimulating chondrocyte metabolism and synthesis of cartilage matrix components while inhibiting enzymes that break down cartilage.
  • Patients may experience mild side effects including injection site reactions or allergic responses.
  • This medication is more commonly used in Eastern European countries and may not be approved in all regions.
  • Before starting treatment, patients should consult with their healthcare provider to determine if Alflutop is appropriate for their specific condition and to establish the optimal dosing schedule. The use of Alflutop has been shown to be effective in various studies, including a study published in 2004 2 which demonstrated its efficacy in relieving pain and improving joint function in patients with osteoarthritis. Another study published in 2011 3 showed that Alflutop can be used in combination with other treatments, such as peloid applications, to achieve better results. Additionally, a study published in 2005 4 demonstrated the efficacy of Alflutop in the local therapy of shoulder periarthritis. However, it is essential to note that the most recent and highest quality study 1 should be prioritized when making treatment decisions, as it provides the most up-to-date and reliable evidence on the efficacy and safety of Alflutop.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.