What is the diagnosis for a patient presenting with arthralgia (joint pain) and alopecia (hair loss)?

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Differential Diagnosis for Joint Pain and Hair Loss

  • Single most likely diagnosis:
    • Rheumatoid Arthritis (RA) - This is a common autoimmune disorder that can cause joint pain and inflammation, and some patients may experience hair loss due to the disease itself or as a side effect of treatment.
  • Other Likely diagnoses:
    • Lupus - A chronic autoimmune disease that can cause joint pain, hair loss, and a variety of other symptoms.
    • Psoriatic Arthritis - A type of arthritis that occurs in people with psoriasis, causing joint pain and inflammation, and can also lead to hair loss.
    • Thyroid Disorders (Hypothyroidism or Hyperthyroidism) - Both conditions can cause hair loss and joint pain, among other symptoms.
    • Vitamin Deficiencies (e.g., Vitamin D or B12 deficiency) - Certain vitamin deficiencies can lead to joint pain and hair loss.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.):
    • Cancer (e.g., Lymphoma) - Certain types of cancer can cause joint pain and hair loss, and early diagnosis is crucial for treatment.
    • Sarcoidosis - A rare disease that can cause inflammation in various parts of the body, including the joints, and can lead to hair loss.
    • Autoimmune Hemolytic Anemia - A condition where the immune system attacks red blood cells, which can cause joint pain and hair loss.
  • Rare diagnoses:
    • Alopecia Areata - An autoimmune disorder that causes hair loss, and some patients may experience joint pain.
    • Dermatomyositis - A rare inflammatory disease that can cause skin rash, hair loss, and joint pain.
    • Relapsing Polychondritis - A rare disease that causes inflammation of cartilage and connective tissue, leading to joint pain and hair loss.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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