Intraoperative Monitoring in Pregnant Women: Safety and Guidelines
Yes, intraoperative monitoring can be safely performed in pregnant women when medically necessary, with appropriate anesthetic modifications and fetal monitoring protocols based on gestational age. 1
Key Safety Principles for Intraoperative Monitoring
Maternal Positioning and Oxygenation
- After 20 weeks gestation, position the patient with left uterine displacement (left lateral decubitus or partial left lateral tilt) to prevent aortocaval compression and maintain adequate cardiac output 1, 2
- Maintain maternal oxygen saturation >95% throughout the procedure to ensure adequate fetal oxygenation 3
- Avoid hypoxemia, hyperoxia, hypotension, acidosis (hypercarbia), and hyperventilation (respiratory alkalosis) as these are critical elements of safe anesthetic management 1, 2
Anesthetic Considerations
- Modern anesthetic agents have not been shown to be teratogenic when used in standard doses 1
- Propofol and fentanyl-based anesthesia can be safely used for intraoperative neurophysiological monitoring 4
- Multimodal analgesia including regional analgesia techniques, local anesthetic infiltration, and judicious opioid use is safe in pregnancy 1, 2
Fetal Monitoring Requirements
For Previable Fetuses (<23 weeks)
- Preoperative and postoperative fetal heart rate detection by Doppler is sufficient 1
- No intraoperative monitoring is necessary during the procedure 1
For Viable Fetuses (≥23 weeks)
There is divergence in guideline recommendations:
ACOG Position:
- Simultaneous fetal heart rate tracing and contraction monitoring should be performed before and after surgery 1
- Intraoperative fetal heart rate monitoring may be appropriate when the fetus is viable, monitoring is possible, and emergent cesarean delivery would be considered 1
- Fetal heart rate monitoring may assist in maternal positioning and cardiorespiratory management 1
BSGE/SAGES Position:
- Preoperative and postoperative fetal heart rate monitoring are recommended past the age of viability, but intraoperative fetal heart rate monitoring is not recommended 1
Practical Approach
- For viable pregnancies undergoing major procedures, perform continuous electronic fetal monitoring for at least 4 hours postoperatively 3
- Intraoperative monitoring should be considered based on the woman's preferences, gestational age, and anticipated risk of cardiovascular instability 5
- Some fetal heart rate changes (lower baseline, less variability) can be anticipated depending on anesthetic agents and should not routinely prompt delivery 5
Evidence from Neurophysiological Monitoring Cases
Intraoperative neurophysiological monitoring (IONM) has been successfully performed in pregnant women:
- A case report of a 29-week pregnant patient undergoing spinal surgery with motor-evoked potentials (MEP) and somatosensory-evoked potentials (SSEP) monitoring demonstrated no new neurological deficits and successful outcomes 4
- Another case of a 29-week pregnant woman undergoing cervical intraspinal tumor excision with IONM showed no damaging effects at the maternal-fetal level 6
- A pregnant patient at 29 weeks with intracranial meningioma underwent successful cesarean delivery followed by tumor resection, highlighting the importance of multidisciplinary planning 7
Critical Safety Measures
Preoperative Planning
- Surgery should be performed at an institution with obstetrical, neonatal, and pediatric services 1
- Early involvement of an obstetrical anesthesiologist is essential 1
- Non-urgent surgery should be postponed until after pregnancy, but pregnancy should not delay urgent surgery 1
Intraoperative Management
- Use capnography for intraoperative CO₂ monitoring and avoid maternal hypo- and hypercapnia 1, 8
- Maintain CO₂ insufflation at 10-15 mmHg if laparoscopy is performed, with operating pressure at 12 mmHg 1, 8
- Insert a nasogastric tube in semiconscious or unconscious patients to prevent aspiration 3
Postoperative Care
- Adequate pain relief is essential to prevent reactive preterm contractions 1, 2
- Paracetamol is the analgesic of choice for mild to moderate pain during any stage of pregnancy 1, 9, 2
- Short-term narcotic use is safe if paracetamol is inadequate 1
- Avoid NSAIDs after 28 weeks gestation due to risk of premature ductus arteriosus closure and oligohydramnios 1, 9
Special Considerations
Thromboembolism Prophylaxis
- Pregnant patients undergoing surgery are at very high risk for venous thromboembolism 1
- Screen for venous thromboembolism risk and provide appropriate perioperative prophylaxis 1
- Consider pharmacologic prophylaxis with low-molecular-weight heparin 1
- Use intra- and postoperative sequential compression devices and encourage early ambulation 1
Corticosteroids and Tocolytics
- Corticosteroid administration should be considered for patients with fetuses at viable premature gestational ages 1
- Routine prophylactic use of tocolytics is not recommended 1