Recreational Ketamine Dosing for Euphoric Effects
I cannot and will not provide guidance on recreational ketamine dosing for the purpose of "getting high," as this represents dangerous drug abuse with significant medical and legal risks.
Why This Question Cannot Be Answered Responsibly
Providing dosing information for recreational ketamine use would be medically and ethically inappropriate, as ketamine abuse carries substantial risks to morbidity and quality of life.
Medical Risks of Recreational Ketamine Use
Acute neuropsychiatric effects include impaired consciousness, dizziness, irrational behavior, hallucinations, dissociative states (derealization and depersonalization), and potentially dangerous behavioral changes 1, 2
Chronic ketamine abuse leads to severe and potentially irreversible complications including:
- Ketamine-induced cystitis (bladder inflammation and damage) requiring multidisciplinary management with pharmacotherapy and potentially surgery 1
- Cholangiopathy (bile duct damage) requiring pain management and biliary stenting 1
- Impaired verbal information processing and cognitive deficits 1
- Genitourinary pain that may persist even after cessation 3
Acute toxicity risks include vomiting with potential aspiration (even with some airway reflex preservation), respiratory depression (especially with rapid administration), enhanced vasopressor response, and laryngospasm 3, 1
Legal and Regulatory Context
Ketamine has become a commonly abused drug over the past decade, particularly associated with dance culture and electronic music events 1, 2
The dissociative states produced by ketamine made it popular as a recreational drug, leading to increased regulation in most countries 4
Ketamine is mentioned as a date-rape drug that produces amnesia, delirium, vivid hallucinations, confusion, and altered consciousness, with effects occurring within 20 minutes 5
Clinical Use vs. Abuse
For context on legitimate medical use only:
- Anesthetic induction doses range from 1-4.5 mg/kg IV (average 2 mg/kg) or 6.5-13 mg/kg IM 3
- Antidepressant/antisuicidal doses are typically 0.2-0.5 mg/kg IV infused over 40 minutes 5, 6
- These doses are administered only in controlled medical settings with continuous monitoring, emergency airway equipment immediately available, and physician supervision 3
Any use of ketamine outside of legitimate medical supervision represents drug abuse with serious health consequences and legal ramifications.