Triamcinolone Dental Paste Application for Canker Sores
Apply triamcinolone acetonide 0.1% dental paste directly to the dried ulcer surface 2-4 times daily, pressing a small amount onto the lesion without rubbing, and avoid eating or drinking for 30 minutes after application.
Application Technique
- Dry the ulcer surface with a cotton swab or gauze before application to ensure proper adhesion of the paste 1, 2
- Apply a thin layer of triamcinolone acetonide 0.1% paste directly to the lesion using a clean finger or cotton-tipped applicator 3, 4
- Press gently onto the ulcer without rubbing to allow the paste to adhere to the mucosa 1
- Avoid eating, drinking, or rinsing for at least 30 minutes after application to maximize mucosal contact time 5
Dosing Frequency
- Use 2-4 times daily depending on severity of symptoms, with applications ideally after meals and at bedtime 2, 3
- For localized, easily accessible ulcers, the paste can be mixed with 50% Orabase and applied twice weekly as an alternative regimen 1, 2
Expected Timeline
- Pain reduction typically begins within 24-48 hours of initiating treatment 3
- Ulcer size reduction becomes noticeable by day 3-5 of consistent application 3
- Complete healing usually occurs within 7-10 days with proper adherence 3, 4
- Continue treatment until the ulcer has completely healed, then discontinue 5
Critical Precautions
- Monitor for oral candidiasis (thrush), which is the most common complication of topical corticosteroid use in the mouth 5
- If white patches or increased burning develop, treat presumptively with nystatin oral suspension or miconazole oral gel 2, 5
- Do not use if there is evidence of oral herpes simplex infection or other active viral/bacterial infections 1
When Topical Treatment Fails
- If no improvement after 7-10 days of proper application, consider intralesional triamcinolone injection (28 mg total dose weekly) in conjunction with continued topical therapy 1, 2
- For highly symptomatic or recurrent ulcers, systemic corticosteroids (30-60 mg oral prednisone for 1 week with tapering) may be necessary 1, 2