What is the augmenting dose (increasing dose) for a 14-year-old child?

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Co-amoxiclav (Augmentin) Dosing for a 14-Year-Old Child

For a 14-year-old child, the standard co-amoxiclav dose is 1 tablet (250 mg amoxicillin/125 mg clavulanate) three times daily for oral therapy, or 1.2 g three times daily for intravenous therapy. 1

Oral Dosing

  • Standard dose: 1 tablet containing 250 mg amoxicillin/125 mg clavulanate, administered three times daily 1
  • Duration: 7-10 days for most infections, though may extend to 14 days depending on clinical response 1
  • Severe infections: Doses may be doubled in severe infections 1

Intravenous Dosing

  • Standard dose: 1.2 g three times daily for patients aged 12-18 years 1
  • Weight-based alternative: 30 mg/kg three times daily (based on co-amoxiclav content) for patients 1 month to 12 years 1
  • Severe infections: Over 3 months of age, dose frequency can be increased to four times daily in severe infections 1
  • Maximum daily dose: 4 g of amoxicillin component (max daily dose 4 g) 1

Clinical Context

The British Thoracic Society guidelines place 14-year-olds in a transitional category, as the dosing table shows "12-14 y" receiving 400 mg for azithromycin, but for co-amoxiclav specifically lists "12-18 y" as receiving the adult tablet formulation 1. This reflects that by age 14, most children can tolerate adult tablet formulations and have reached sufficient body size for adult dosing.

Important Considerations

  • Formulation matters: The 12-18 year age group receives tablet formulations rather than suspensions, which is appropriate for a 14-year-old 1
  • Treatment duration: Continue therapy for 7-10 days minimum, with extension to 14 days based on clinical response 1
  • Route selection: IV therapy is reserved for patients unable to tolerate oral medications or those requiring hospitalization; transition to oral therapy should occur based on clinical response and ability to tolerate oral treatment 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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