What are examples of hydrogels used in wound care?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: December 1, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Hydrogels in Wound Care

Hydrogels are water-based gel dressings specifically designed for dry or necrotic wounds that require moisture to facilitate autolytic debridement and healing. 1

What Hydrogels Are

Hydrogels are advanced wound dressings characterized by their high water content and gel-like consistency that provide moisture to the wound bed. 1, 2 They function as autolytic debridement agents by hydrating dry, necrotic tissue and facilitating the body's natural enzymatic breakdown of dead tissue. 1, 2

Primary Clinical Applications

Hydrogels should be used for:

  • Dry wounds requiring hydration 1, 2
  • Necrotic wounds where autolytic debridement is needed 1
  • Wounds with minimal exudate (they provide moisture rather than absorb it) 2

Key Clinical Properties

Hydrogels promote epithelialization and reduce pain through their moisture-retentive properties. 1 They create a hospitable, moist environment that allows cells to thrive while still permitting the wound to breathe and drain exudate. 3 These dressings tend to have a soothing effect and are generally less painful for patients. 3

Important Limitations and Contraindications

Do not use hydrogels in the following situations:

  • Heavily exuding wounds - hydrogels will cause maceration of surrounding tissue 2
  • Infected wounds - the moist environment may promote bacterial growth 2
  • As primary treatment for diabetic foot ulcers - sharp debridement is strongly preferred over hydrogel-based autolytic debridement 1, 2

The evidence supporting hydrogels for wound healing is of low quality with high risk of bias in published studies. 1, 2

Comparison with Other Dressing Types

Select dressings based on wound characteristics:

  • Hydrocolloid dressings: Better for minimal to moderate exudate wounds 2, 4
  • Foam dressings: More appropriate for moderate to heavy exudate 2, 4
  • Alginate dressings: For drying exudative wounds 1
  • Film dressings: For dry wounds with minimal exudate, similar indication to hydrogels 2, 4

Dressings should be selected primarily based on exudate control, comfort, and cost rather than advanced properties. 1, 2, 4

Application Technique

  • Clean the wound with water or saline before applying hydrogel 2
  • Apply hydrogel directly to the wound bed ensuring complete contact 2
  • Cover with an appropriate secondary dressing to secure the hydrogel 2
  • Change dressings daily to once weekly depending on wound condition 2
  • Monitor for signs of infection or maceration of surrounding skin 2

Common Pitfalls to Avoid

Do not use topical antimicrobials in hydrogel dressings for clinically uninfected wounds - they do not improve healing outcomes. 1 Avoid using hydrogels as a substitute for sharp debridement in diabetic foot ulcers, where sharp debridement remains the gold standard despite hydrogels' theoretical benefits. 1, 2

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Hydrogel Dressings in Wound Care

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Absorbent Acrylic Dressing for Healing Biopsy Site

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.