What is the proper procedure for reading and interpreting an electrocardiogram (EKG)?

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Last updated: December 1, 2025View editorial policy

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Systematic Approach to EKG Interpretation

Use a structured, stepwise method to interpret every EKG, systematically evaluating rate, rhythm, axis, intervals, and waveform morphology to avoid missing critical diagnoses. 1

Step 1: Calculate Heart Rate

  • Count the number of QRS complexes in a 6-second strip and multiply by 10, or use the formula 300 divided by the number of large boxes between consecutive R waves 1, 2
  • Normal sinus rhythm ranges from 60-100 beats per minute in adults 2
  • Sinus bradycardia (<60 bpm) may be normal in athletes, while sinus tachycardia (>100 bpm) can occur during physiological stress 2

Step 2: Assess Rhythm and Regularity

  • Identify the underlying rhythm by examining P wave morphology and its relationship to QRS complexes 1
  • Sinus rhythm is characterized by a P wave before each QRS complex with consistent PR interval 2
  • Evaluate R-R intervals for consistency to determine rhythm regularity 1
  • Note any irregularities such as premature beats, pauses, or completely irregular patterns that might suggest atrial fibrillation 2

Step 3: Measure Critical Intervals

  • Measure the PR interval (normal: 120-200 ms or 3-5 small squares) to assess AV conduction 1, 2
  • Measure QRS duration (normal: <120 ms or <3 small squares) to evaluate ventricular conduction 1, 2
  • Calculate QTc using Bazett's formula (normal: <450 ms for men, <460 ms for women) to assess repolarization 1, 2
  • Identify any conduction abnormalities such as AV blocks, bundle branch blocks, or pre-excitation 2

Step 4: Determine Electrical Axis

  • Examine leads I and aVF to quickly determine the axis quadrant 1
  • Normal axis: -30° to +90° (positive in both leads I and aVF) 2
  • Left axis deviation: -30° to -90° (positive in lead I, negative in aVF) 2
  • Right axis deviation: +90° to +180° (negative in lead I, positive in aVF) 2

Step 5: Analyze Waveform Morphology

P Waves

  • Examine P wave morphology (normal: upright in I, II, aVF; biphasic in V1) 1
  • Evaluate P wave duration (<120 ms) and amplitude (<2.5 mm) 1
  • Assess for atrial enlargement patterns 2

QRS Complexes

  • Analyze QRS morphology for pathologic Q waves (>1 mm wide and >1/3 the height of the R wave or >0.04 seconds) suggesting myocardial infarction 1, 2
  • Assess R wave progression across precordial leads (amplitude increases from V1 to V4, then decreases toward V6) 1
  • Look for voltage criteria for left ventricular hypertrophy: S in V1 + R in V5 or V6 >3.5 mV 2

ST Segments and T Waves

  • Examine ST segments for elevation (>0.1 mV in limb leads or >0.15-0.2 mV in precordial leads) or depression that may indicate ischemia or injury 1, 2
  • Assess T wave morphology (normally upright in leads I, II, V3-V6; inverted in aVR; variable in III, aVL, aVF, V1, V2) 1
  • Look for T-wave abnormalities including inversion, hyperacute changes, or flattening 2

Step 6: Identify Location of Abnormalities

  • Note the location of ST-segment or T-wave abnormalities to determine the affected coronary territory 2
  • Correlate findings with clinical presentation to assess for acute coronary syndrome 1

Critical Pitfalls to Avoid

  • Never rely solely on computer interpretation without physician verification, as computer programs perform less well than expert readers and errors remain common 3, 2
  • Avoid misplacement of electrodes, particularly precordial leads, which can significantly alter interpretation and lead to false diagnoses 2
  • Do not interpret the EKG in isolation—always consider the patient's clinical presentation, as the same finding may have different implications depending on symptoms 2
  • Always compare with previous EKGs when available to identify significant changes 2
  • Be aware that inadequate filtering settings can distort waveforms and affect measurements 2

Special Considerations

  • Age and gender affect normal EKG parameters—QT intervals are typically longer in women, and QRS voltage criteria decline with age 1, 2
  • Certain medications (antiarrhythmics, psychotropics) can affect EKG findings 1
  • T waves are often inverted in leads V1, V2, and V3 in children older than 1 month 2
  • Athletes may demonstrate normal variants including sinus bradycardia (≥30 beats/min) 2

Quality Assurance

  • All computer-based EKG reports require physician overreading, as computer interpretation is only an adjunct to the electrocardiographer 3
  • Evaluate the quality of the EKG recording and identify any technical artifacts that may affect interpretation 2
  • Consider continuing medical education through seminars or self-assessment programs to maintain current EKG interpretation skills 2

References

Guideline

ECG Interpretation Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

EKG Interpretation Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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