What is the differential diagnosis (Ddx) of rectal bleeding?

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Differential Diagnosis for Rectal Bleeding

The following is a differential diagnosis for rectal bleeding, categorized for clarity and emphasis on potential severity.

  • Single Most Likely Diagnosis
    • Hemorrhoids: This is the most common cause of rectal bleeding, especially in adults. Hemorrhoids are swollen veins in the rectum or anus that can cause bleeding, pain, and discomfort.
  • Other Likely Diagnoses
    • Anal Fissure: A tear in the lining of the anus can cause pain and bleeding during bowel movements.
    • Diverticulosis: A condition where small, bulging pouches (diverticula) develop in the digestive tract, most commonly in the colon, which can bleed.
    • Inflammatory Bowel Disease (IBD): Conditions like Crohn's disease and ulcerative colitis can cause chronic inflammation and bleeding in the digestive tract.
    • Gastrointestinal Infections: Infections such as gastroenteritis can cause rectal bleeding, especially in children and immunocompromised individuals.
  • Do Not Miss Diagnoses
    • Colorectal Cancer: Although less common, rectal bleeding can be a symptom of colorectal cancer, making it crucial not to miss this diagnosis, especially in older adults or those with a family history.
    • Angiodysplasia: Vascular malformations in the colon can cause bleeding, often in older adults.
    • Ischemic Colitis: Reduced blood flow to the colon can cause bleeding and is a medical emergency.
    • Intussusception: A condition where a part of the intestine slides into an adjacent part, potentially cutting off blood supply and causing bleeding, more common in children but can occur in adults.
  • Rare Diagnoses
    • Rectal Ulcer: An open sore in the rectum can cause bleeding and pain.
    • Solitary Rectal Ulcer Syndrome: A condition causing rectal bleeding and pain due to a ulcer in the rectum, often associated with chronic constipation.
    • Dieulafoy's Lesion: A rare cause of gastrointestinal bleeding due to a small mucosal defect with an exposed artery.
    • Vasculitis: Inflammation of the blood vessels can cause rectal bleeding, among other symptoms, and is associated with various autoimmune conditions.

Each of these diagnoses has distinct characteristics and risk factors, and a thorough medical history, physical examination, and diagnostic tests are necessary to determine the cause of rectal bleeding in an individual.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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