Usual Directions for Patient Mouthwash
For general oral hygiene, patients should rinse, swish, and spit with a bland saline rinse (1 teaspoon salt, 1 teaspoon baking soda in 4 cups of water) several times a day, holding the solution in the mouth before expectorating. 1
Basic Mouthwash Technique
- Rinse the oral cavity vigorously to maintain moisture, remove debris, and reduce plaque and infection accumulation 1
- Swish and spit the mouthwash solution—do not swallow 1
- Perform rinsing several times daily as needed with the basic saline rinse 1
Antiseptic Mouthwash (Chlorhexidine)
When an antiseptic mouthwash is prescribed:
- Use 10 mL of 0.2% chlorhexidine digluconate twice daily 1
- Rinse for approximately 30-60 seconds before spitting out 2
- Diluting 0.2% chlorhexidine by up to 50% can reduce soreness while maintaining effectiveness 1
- Avoid eating or drinking for 30 minutes after use to maximize efficacy 2
Important Caveats for Chlorhexidine
- Expect extrinsic tooth staining as a common side effect with use beyond 4 weeks 2
- Other potential side effects include taste disturbance, oral mucosa irritation, and burning sensation 2, 3
- Alcohol-free formulations are preferred for high-risk populations including children, those with alcohol dependency, and patients with genetic deficiencies in ethanol metabolism 1, 4
Anti-inflammatory Mouthwash
For oral inflammation or pain:
- Use benzydamine hydrochloride rinse or spray every 3 hours, particularly before eating 1
- Alternative topical anesthetic: viscous lidocaine 2%, 15 mL per application, may be used if benzydamine is inadequate 1
Mucoprotectant Mouthwash
For ulcerated mucosal surfaces:
- Use a mucoprotectant mouthwash three times daily (such as products designed to coat and protect ulcerated areas) 1
What to Avoid
- Do not use commercial mouthwashes with alcohol base or astringent properties for patients with oral complications 1
- Avoid glycerin or lemon-glycerin swabs as they dry the mouth rather than moisturize 1
- Club soda should be avoided due to carbonic acid content 1
Timing and Retention
- Retain the preparation in the mouth as long as possible before swallowing (for antifungal suspensions) 5
- For general oral hygiene, brush within 30 minutes after eating and before bed 1
- Use prescription-strength fluoride toothpaste; spit out foam but do not rinse mouth immediately after brushing to maximize fluoride contact 1
Common Pitfalls
- Rinsing immediately after fluoride toothpaste reduces its effectiveness—patients should spit but not rinse 1
- Using mouthwash as a substitute for mechanical cleaning (brushing and flossing) is ineffective, as mouthwashes cannot penetrate established plaque biofilm 6
- Prolonged chlorhexidine use without patient counseling about staining leads to poor compliance 2, 3