From the Research
Relationship between H. pylori infection and skin manifestations
- There is evidence indicating the role of Helicobacter pylori infection in the pathogenesis of extragastrointestinal diseases, including skin disorders 1, 2.
- The occurrence of dermatological disorders has been related to H. pylori infection, although the exact mechanisms are not fully understood 1.
- Some studies have investigated the association between H. pylori infection and various extragastric diseases, including skin manifestations, but the results are not conclusive 2, 3.
- Further studies are needed to explore the relationship between H. pylori infection and skin manifestations, as well as the potential pathogenic mechanisms underlying this association.
Potential pathogenic mechanisms
- The activation of pro-inflammatory cytokines by H. pylori might be a possible pathogenetic mechanism underlying the relationship between H. pylori infection and extragastric diseases, including skin disorders 3.
- The H. pylori-associated inflammation may lead to increased insulin resistance, and potentially influence the development of various extragastric diseases, including skin manifestations 1.
- The relationship between H. pylori infection and skin manifestations may be influenced by various factors, including the host's immune response, the presence of other comorbidities, and the severity of the infection 4.