Optimal Ultrasound Probe Selection for Ruling Out Placenta Accreta
A combination of transvaginal ultrasound with transabdominal ultrasound using a high-frequency (5-9 MHz) linear probe when body habitus permits is the best approach to rule out placenta accreta, with transvaginal ultrasound being essential for detailed evaluation of the anterior lower uterine segment and myometrial-placental interface. 1
Primary Probe Recommendations
Transvaginal Ultrasound (Essential)
- Transvaginal scanning must be used in conjunction with transabdominal scanning to provide the highest-resolution evaluation of the anterior lower uterine segment myometrium, placenta, and myometrial-placental interface 1
- Transvaginal ultrasound with color Doppler has demonstrated superior diagnostic accuracy, with studies showing correct identification of all placenta accreta cases when combined with color flow studies 2
- This approach is particularly critical for evaluating the cesarean scar area and lower uterine segment where most accreta cases occur 1
Transabdominal High-Frequency Linear Probe (When Feasible)
- A high-frequency (5-9 MHz) linear probe should be used transabdominally if body habitus allows, as it permits focused evaluation of uterine and placental morphology with superior resolution 1
- The linear probe provides better visualization of the retroplacental clear zone and myometrial thickness compared to standard curvilinear probes 1
Technical Considerations for Optimal Imaging
Bladder Preparation
- The bladder must be at least moderately full (200-300 mL) to properly identify and evaluate the lower uterine segment and cesarean section scar area 1
- An empty bladder prevents appropriate evaluation for bladder wall interruption, placental bulge, and uterovesical hypervascularity 1
Scanning Technique
- Assess the retroplacental clear zone without excessive probe pressure to prevent artifactual loss of this important diagnostic marker 1
- This is a critical pitfall to avoid, as excessive pressure can create false-positive findings 1
Doppler Enhancement
Color and Power Doppler Integration
- Adding color Doppler and power Doppler imaging significantly improves detection of placenta accreta by identifying increased placental vascular flow, subplacental vascularity, and vessels bridging from placenta to bladder 1
- Power Doppler ultrasound performed particularly well in diagnosing lower-uterine-segment placenta accreta in validation studies 3
- Turbulent lacunar blood flow is the most common and helpful Doppler finding for placenta accreta 1
Three-Dimensional Color Doppler
- Three-dimensional color Doppler showing "numerous coherent vessels" involving the placental base demonstrated 97% sensitivity and 92% specificity for placenta accreta 1
Key Diagnostic Features to Assess
Most Sensitive Gray-Scale Findings
- Intraplacental lacunae (multiple, large, irregular sonolucent spaces with turbulent flow) have the highest sensitivity and positive predictive value for placenta accreta 1, 4
- Loss of the normal hypoechoic retroplacental clear zone 1, 4
- Myometrial thickness <1 mm 1, 5
Most Specific Findings
- Disruption of the placental-uterine wall interface with vessels crossing these disruption sites showed the highest specificity (98%) in diagnostic studies 5
- Interruption, thickening, or irregularity of the uterine serosa-bladder interface has high sensitivity and specificity, particularly as invasion depth progresses 1
- Increased vascularization at the uterine serosa-bladder wall interface and perpendicular vascularization to the uterine wall had 92% positive predictive value 4
Common Pitfalls and Limitations
False-Positive Considerations
- Loss of retroplacental clear zone as an isolated finding has only 52% sensitivity and 57% specificity with a 21% false-positive rate, as normal anterior placentas may also lack this zone 1
- Never rely on a single finding; multiple concordant features are required for diagnosis 1
Posterior Placenta Limitation
- When the placenta is posterior or not low-lying, ultrasound assessment becomes more challenging 1
- In these cases, MRI may be complementary, particularly for posterior placenta accreta 3, 4, 6
Diagnostic Performance
Overall Ultrasound Accuracy
- Ultrasound sensitivity ranges from 77% to 93% with positive predictive value of 65% to 93% when performed with appropriate technique 1
- A systematic review of 3,707 pregnancies demonstrated average sensitivity of 90.72% and specificity of 96.94% for ultrasound diagnosis 1
- Ultrasound demonstrated 100% sensitivity in one comparative study versus 76.9% for MRI 4