Which tendons are affected by De Quervain tenosynovitis?

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De Quervain Tenosynovitis: Affected Tendons

De Quervain tenosynovitis affects the abductor pollicis longus (APL) and extensor pollicis brevis (EPB) tendons within the first dorsal compartment of the wrist. 1, 2, 3, 4

Primary Tendons Involved

The condition specifically involves stenosing tenosynovitis of two tendons that pass through the first dorsal compartment:

  • Abductor pollicis longus (APL): This tendon abducts the thumb and is consistently involved 3, 5, 4
  • Extensor pollicis brevis (EPB): This tendon extends the thumb at the metacarpophalangeal joint 3, 5, 4

Both tendons become inflamed within their shared fibro-osseous canal on the radial (thumb) side of the wrist, causing the characteristic pain with resisted gliding 4.

Anatomical Variations to Consider

Anatomical variations within the first dorsal compartment are common and clinically significant:

  • Subcompartmentalization occurs in approximately 79% of patients with de Quervain tenosynovitis, where a septum divides the first dorsal compartment into separate channels for the APL and EPB 6
  • Accessory APL tendons are frequently present, with some patients having multiple APL slips 7, 5, 6
  • Ultrasound can identify these variations, showing thickened, hypoechoic tenosynovial sheath surrounding the tendons and detecting septations that affect surgical planning 8, 2, 5

Clinical Pitfalls

Failure to recognize anatomical variations leads to treatment failure:

  • Subcompartments must be identified during surgical release, as incomplete release of all compartments results in persistent symptoms 7, 6
  • Accessory tendons can be at risk for subluxation over bony prominences if not properly addressed 7
  • The American College of Radiology recommends ultrasound for confirming diagnosis and identifying these variants when surgical planning is needed 2

References

Guideline

Management of De Quervain's Tenosynovitis

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Diagnostic Approach for De Quervain's Tenosynovitis

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Results of injection corticosteroids in treatment of De Quervain's Tenosynovitis.

JPMA. The Journal of the Pakistan Medical Association, 2014

Research

De quervain tenosynovitis of the wrist.

The Journal of the American Academy of Orthopaedic Surgeons, 2007

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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