From the FDA Drug Label
Hydrastis canadensis 1M Less than 10 -12 mg hydrastine, berberine alkaloids per pellet (**contains 0.443 mg of the active ingredient per pellet)
- Berberine is an alkaloid, as indicated by the presence of berberine alkaloids in the drug label 1.
- It is an active ingredient in the mentioned pellet, with a specified amount of 0.443 mg per pellet.
- The drug label does not provide a detailed definition or description of berberine, but it implies that berberine is a component of the drug.
From the Research
Berberline is not a recognized medical term or medication, and it appears to be a misspelling of berberine, which is a natural compound found in several plants including barberry, goldenseal, and Oregon grape. Berberine is used as a dietary supplement for various conditions including high cholesterol, diabetes, and digestive issues. It typically comes in capsule form with dosages ranging from 500-1500 mg daily, divided into 2-3 doses. If you're considering using berberine, it's essential to consult with a healthcare provider first, especially if you're taking other medications, as berberine can interact with certain drugs 2. The compound works by activating an enzyme called AMP-activated protein kinase (AMPK), which helps regulate metabolism and may improve insulin sensitivity. Some of the key benefits of berberine include:
- Anti-inflammatory, antioxidant, and immunomodulatory effects 2
- Glucose-lowering effect, which is related to the baseline fasting plasma glucose and hemoglobin A1c levels of patients 3
- Improvement in lipid metabolism, with significant decreases in plasma triglycerides and low-density lipoprotein cholesterol 4
- Protective effects against various diseases, including cancer, digestive, metabolic, cardiovascular, and neurological diseases 5 Side effects can include digestive discomfort, so starting with a lower dose and taking it with food is often recommended. It's crucial to note that while berberine has shown promising results, more studies are needed to elucidate the optimal doses, safety profiles, and potential interactions of berberine with other drugs or natural compounds 2.