Feropenem Information Not Available in Provided Evidence
The provided evidence does not contain any information about Feropenem. All references discuss other carbapenem antibiotics (meropenem, imipenem, doripenem, ertapenem) but do not mention Feropenem specifically.
What the Evidence Does Cover
The evidence extensively covers meropenem, which is a different carbapenem antibiotic, with the following standard dosing:
Meropenem Dosing (Not Feropenem)
- Standard dose: 1 gram IV every 8 hours for serious infections in adults with normal renal function 1, 2
- Extended infusion (3 hours) is recommended for critically ill patients or when treating organisms with MIC ≥8 mg/L 2
- Treatment duration: 5-7 days for complicated intra-abdominal infections with adequate source control 2
- 7-14 days for bloodstream infections 2
Clinical Context for Carbapenems (General Class)
- Used for community-acquired intra-abdominal infections in patients at risk for ESBL-producing Enterobacteriaceae 1
- Used for healthcare-associated infections with multidrug-resistant organisms 1
- Often combined with ampicillin 2 grams every 6 hours for enterococcal coverage in high-risk patients 1, 2
Critical Note
Feropenem is a distinct carbapenem antibiotic that is not addressed in any of the provided guidelines or research studies. To obtain accurate dosing and usage information for Feropenem specifically, you would need to consult its FDA drug label, product monograph, or specific clinical studies evaluating this agent.