What is the starting dose of Climax (climacteric), also known as menopause, treatment?

From the Research

The starting dose of dapoxetine for premature ejaculation is 30 mg taken on demand, 1-3 hours before planned sexual activity, as it has been shown to be effective and safe in improving intravaginal ejaculatory latency time (IELT) and patient-reported outcomes 1, 2.

Key Considerations

• Dapoxetine is a potent selective serotonin reuptake inhibitor (SSRI) that is rapidly absorbed and eliminated, resulting in minimal accumulation and dose-proportional pharmacokinetics 3.
• The 30 mg dose of dapoxetine has been evaluated in several randomized, double-blind, placebo-controlled studies and has been shown to be effective in improving IELT and patient-reported outcomes, with a high likelihood of being the "best" treatment option 1.
• The most common adverse events associated with dapoxetine include nausea, dizziness, and headache, but the incidence of these events is generally low and the drug is well-tolerated 3, 2.

Dosing and Administration

• The recommended starting dose of dapoxetine is 30 mg taken on demand, 1-3 hours before planned sexual activity 3, 1.
• The dose can be adjusted based on response and tolerability, but the 30 mg dose has been shown to be effective and safe in most patients 1, 2.

Special Considerations

• For patients with liver impairment or other underlying medical conditions, a lower starting dose or more gradual titration may be necessary 3.
• Dapoxetine should not be taken with other SSRIs or certain other medications, as this can increase the risk of adverse events 3, 4.