What conditions, besides Urinary Tract Infection (UTI), can cause dysuria and suprapubic pain?

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Differential Diagnosis for Dysuria and Suprapubic Pain

Single Most Likely Diagnosis

  • Urinary Tract Infection (UTI): This is the most common cause of dysuria and suprapubic pain, especially in women. The symptoms are classic for a lower urinary tract infection, which includes cystitis.

Other Likely Diagnoses

  • Vaginitis: Inflammation of the vagina, often due to infection, can cause dysuria, especially if the inflammation involves the urethral meatus.
  • Urethral Syndrome: A condition characterized by symptoms of a UTI without evidence of infection, possibly due to urethral irritation or inflammation.
  • Interstitial Cystitis: A chronic condition causing bladder pressure, bladder pain, and sometimes pelvic pain, which can mimic the symptoms of a UTI.
  • Kidney Stones: While often associated with flank pain, small stones or stones in the distal ureter can cause suprapubic pain and dysuria.

Do Not Miss Diagnoses

  • Appendicitis: Although appendicitis typically presents with right lower quadrant pain, an inflamed appendix located near the bladder or ureter can cause suprapubic pain and dysuria.
  • Ectopic Pregnancy: A pregnancy developing outside the uterus can cause severe abdominal pain, including suprapubic pain, and if it involves the urinary system, dysuria.
  • Diverticulitis: Inflammation of a diverticulum in the sigmoid colon can cause left lower quadrant pain but can also refer pain to the suprapubic area if the inflammation involves the bladder or ureter.
  • Ovarian Cyst or Torsion: These conditions can cause severe pelvic pain that might be referred to the suprapubic area and could potentially irritate the urinary tract, causing dysuria.

Rare Diagnoses

  • Bladder Cancer: While rare, especially in younger populations, bladder cancer can cause symptoms similar to those of a UTI, including dysuria and suprapubic pain.
  • Schistosomiasis: A parasitic infection that can involve the bladder, causing chronic inflammation, dysuria, and suprapubic pain, more common in travelers to or natives of endemic areas.
  • Tuberculosis of the Urinary Tract: A rare condition in many parts of the world, it can cause chronic symptoms including dysuria, suprapubic pain, and systemic symptoms like weight loss and fever.
  • Endometriosis: Although primarily causing pelvic pain related to menstruation, in rare cases, endometrial implants can involve the bladder, leading to dysuria and suprapubic pain, especially during menses.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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