What does a pacemaker setup as VVI mean in terms of pacing and sensing for a patient with symptomatic bradycardia?

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VVI Pacemaker Function

A VVI pacemaker paces the ventricle, senses the ventricle, and is inhibited by sensed ventricular activity—the correct answer is D.

Understanding the VVI Pacing Code

The three-letter pacemaker code describes the chamber paced, chamber sensed, and response to sensing:

  • First V (Ventricle): The pacemaker delivers electrical impulses to the ventricle 1
  • Second V (Ventricle): The device senses intrinsic ventricular electrical activity 1
  • I (Inhibited): When the pacemaker detects spontaneous ventricular activity, it inhibits its pacing output and does not deliver an unnecessary impulse 1

Clinical Characteristics of VVI Pacing

VVI is described as "the classic prototypical pacing mode" where ventricular pacing is inhibited by sensed spontaneous ventricular activity 1. This means:

  • The pacemaker continuously monitors for intrinsic ventricular depolarization 1
  • If the patient's own ventricular rate exceeds the programmed lower rate limit, the pacemaker remains inhibited and does not pace 2
  • If no ventricular activity is sensed within the programmed interval, the pacemaker delivers a ventricular pacing stimulus 1

Appropriate Clinical Indications

VVI pacing is particularly indicated for symptomatic bradyarrhythmias when 1:

  • There is no significant atrial hemodynamic contribution (such as in persistent or paroxysmal atrial flutter/fibrillation) 1
  • Pacing simplicity is a priority in cases of advanced age, terminal disease, or remote domicile from follow-up centers 1
  • There is absent retrograde ventriculoatrial conduction 1

Important Clinical Caveat

VVI pacing is contraindicated when pacemaker syndrome is present or anticipated 1. Pacemaker syndrome includes light-headedness, syncope, or symptoms related to loss of AV synchrony, inadequate cardiac output from VA conduction, or patient awareness of beat-to-beat variations 1. In such cases, dual-chamber pacing modes that preserve AV synchrony should be considered instead 1.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Ventricular Paced Rhythm with Intrinsic Complexes: Clinical Significance

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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