Can a patient take Iberet 2 tablets once a day?

Iberet Dosing: Standard Once-Daily Administration is Appropriate

Iberet can be taken as 2 tablets once daily, though the standard recommended dosing is 1 tablet once daily for iron deficiency anemia treatment. 1

Standard Dosing Regimen

• The typical prescribed dose of Iberet (or Iberet Folic) is 1 tablet once daily for treatment of iron deficiency anemia in pregnancy. 1
• Taking 2 tablets once daily represents a doubled dose that may be considered in cases of more severe iron deficiency, though this should be discussed with the prescribing physician. 1
• The once-daily formulation is designed to provide sustained iron supplementation throughout the day with a single dose. 1

Efficacy and Safety Profile

• Iberet Folic demonstrated a mean hemoglobin increase of 2.15 g/dL over 30 days when taken as 1 tablet daily, with significant improvement in iron deficiency anemia. 1
• Serum ferritin levels increased by a mean of 8.44 µg/L over the same treatment period with once-daily dosing. 1

Common Adverse Effects to Anticipate

• Gastrointestinal intolerance occurs in approximately 34.6% of patients taking Iberet, making it the most common side effect. 1
• Constipation affects approximately 29.2% of patients on Iberet therapy. 1
• These side effects are comparable to other iron supplementation products and are generally manageable. 1

Clinical Considerations for Doubled Dosing

• If considering 2 tablets once daily (doubled dose), expect potentially higher rates of GI side effects, particularly constipation and nausea. 1
• The doubled dose may be warranted in severe iron deficiency anemia (hemoglobin <9 g/dL or ferritin <10 µg/L), but this should be based on laboratory values and clinical assessment.
• Monitor for increased GI intolerance with higher doses, and consider dose reduction if side effects become intolerable. 1

Practical Administration Advice

• Take Iberet on an empty stomach (1 hour before or 2 hours after meals) for optimal iron absorption, unless GI side effects are prohibitive.
• If GI side effects occur with 2 tablets once daily, consider splitting to 1 tablet twice daily or reducing to the standard 1 tablet once daily. 1
• Avoid taking with calcium supplements, antacids, or dairy products, which can significantly reduce iron absorption.