Is Mycoplasma plasma contagious?

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Last updated: April 3, 2025View editorial policy

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From the Guidelines

Yes, Mycoplasma is contagious, and it spreads through respiratory droplets when an infected person coughs or sneezes, with close, prolonged contact with an infected individual increasing transmission risk. The bacteria can cause respiratory infections like "walking pneumonia," with symptoms including persistent cough, fatigue, sore throat, and mild fever 1. Most infections resolve on their own within a few weeks, but antibiotics like azithromycin (typically 500mg on day 1, then 250mg daily for 4 more days) or doxycycline (100mg twice daily for 7-14 days) may be prescribed for more severe cases 1. To prevent spread, practice good hygiene including regular handwashing, covering coughs and sneezes, avoiding sharing personal items, and staying home when sick. Mycoplasma bacteria lack cell walls, which makes them naturally resistant to certain antibiotics like penicillins, but responsive to macrolides and tetracyclines.

Some key points to consider:

  • Mycoplasma pneumoniae is a common cause of community-acquired pneumonia, especially in younger adults 1.
  • The diagnosis of Mycoplasma pneumoniae infection is often based on clinical presentation and laboratory tests, such as PCR or serology 1.
  • Treatment with macrolides or doxycycline is usually effective, but antibiotic resistance is a growing concern 1.
  • Prevention of Mycoplasma pneumoniae infection relies on good hygiene practices, such as regular handwashing and avoiding close contact with infected individuals 1.

Overall, the most effective way to manage Mycoplasma pneumoniae infection is through a combination of good hygiene practices, prompt diagnosis, and appropriate antibiotic treatment.

From the Research

Mycoplasma Genitalium Contagion

  • Mycoplasma genitalium is a sexually transmitted infection that can be spread through direct mucosal contact 2.
  • The infection can cause symptoms such as urethritis, dysuria, and discharge in men, and vaginal discharge, dysuria, and pelvic inflammatory disease (PID) in women 2.
  • Asymptomatic infections are frequent, and symptoms are the main indication for diagnostic testing 2.
  • The infection can be diagnosed through nucleic acid amplification testing, and treatment is indicated if the infection is detected 2.

Transmission and Prevention

  • The transmission of Mycoplasma genitalium occurs through direct mucosal contact, highlighting the importance of safe sex practices to prevent the spread of the infection 2.
  • There is no evidence to suggest that Mycoplasma genitalium can be spread through casual contact or airborne transmission 2, 3, 4, 5, 6.

Research Limitations

  • There are limited studies on the contagion of Mycoplasma genitalium, and more research is needed to fully understand the transmission dynamics of the infection 2, 3, 4, 5, 6.
  • The available studies focus primarily on the treatment and diagnosis of Mycoplasma genitalium, rather than its contagion 2, 3, 4, 5, 6.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

2021 European guideline on the management of Mycoplasma genitalium infections.

Journal of the European Academy of Dermatology and Venereology : JEADV, 2022

Research

Mycoplasma pneumonia and its complications.

Infectious disease clinics of North America, 2010

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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