From the FDA Drug Label
Purpose Cough suppressant The FDA drug label does not answer the question.
From the Research
For a 24-year-old male with a secretive cough and history of inactive hepatitis B, I recommend a regimen of dextromethorphan (DXM) as the first-line treatment, as it undergoes minimal hepatic metabolism and is generally safe for patients with liver history 1, 2. The patient's history of inactive hepatitis B is crucial in selecting a treatment regimen that minimizes the risk of hepatitis B reactivation.
- Start with dextromethorphan 30mg every 6-8 hours as needed, not exceeding 120mg in 24 hours.
- This can be taken as an over-the-counter preparation like Robitussin DM or a generic equivalent.
- For nighttime cough relief, consider adding a single dose of diphenhydramine 25mg before bedtime.
- This regimen should be limited to 7-10 days; if the cough persists beyond this period, medical evaluation is necessary. It's essential to avoid medications with significant liver metabolism, such as codeine, to minimize the risk of liver damage or hepatitis B reactivation 3, 4.
- Ensure adequate hydration with 2-3 liters of water daily and consider using a humidifier at night to moisturize airways.
- If the cough is accompanied by other symptoms like fever, chest pain, or shortness of breath, immediate medical attention is warranted rather than self-treatment.