What are the most common causes of injury or death in children?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: December 4, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Most Common Causes of Injury or Death in Children

Injury is the number one killer of children ages 1 to 18 years in the United States, accounting for more deaths than all other causes combined. 1

Age-Specific Leading Causes

Infants (Under 1 Year)

  • Sudden Infant Death Syndrome (SIDS) remains a significant contributor to infant mortality 1
  • Suffocation deaths have increased by 20% from 2010-2011 to 2018-2019, driven in part by better death investigation that now classifies more sleep-related deaths as suffocation events 2, 3
  • Head injuries from falls account for 92% of shopping cart-related injuries in this age group 4

Young Children (1-4 Years)

  • Drowning is the leading cause of death, representing the single most common mechanism of fatal injury 4
  • Unintentional injuries overall account for 12.6% of deaths in this age group 5
  • Shopping cart-related injuries affect 85% of children under 5 years, with 79% involving head and neck injuries 4

School-Age Children (5-14 Years)

  • Drowning is the second leading cause of death from unintentional injury 4
  • Motor vehicle crashes become increasingly important as children age 1, 6
  • Unintentional injuries are the clear leading cause of death 1

Adolescents (15-19 Years)

  • Motor vehicle crashes are the single most common mechanism of death, causing approximately 2,500-fold more deaths than cardiovascular causes 4, 1
  • Suicide is the second leading cause of death, with firearms accounting for a significant proportion 4, 1
  • Homicide is the third leading cause, with 84.5% being firearm-related 1
  • Proportionate mortality from injuries increases to 28.8% in this age group 5

Specific Injury Mechanisms by Frequency

Top Three Fatal Mechanisms (All Ages Combined)

  1. Motor vehicle occupant injuries - most common overall cause of unintentional injury death 6, 7
  2. Drowning - third leading cause of death from unintentional injury worldwide, accounting for 7% of all injury-related deaths 4
  3. Pedestrian injuries - third most common mechanism after motor vehicle and drowning 7

Other Important Mechanisms

  • Poisoning - increasing among children, particularly prescription opioid misuse and overdose 3
  • Burns and fires - significant contributor, especially in low- and middle-income countries 6, 5
  • Falls - common cause of non-fatal injury requiring emergency department visits 6

Critical Demographic Disparities

Sex Differences

  • Male children have significantly higher injury death rates than females (11.3 vs. 6.6 per 100,000 population) 2
  • The exception is burns, which occur more frequently among females in low- and middle-income countries 5

Racial and Ethnic Disparities

  • American Indian/Alaska Native children have the highest death rates (19.4 per 100,000) 2
  • Black children have elevated rates (12.4 per 100,000) and experienced a 9% increase in motor vehicle traffic deaths and 37% increase in poisoning deaths from 2010-2019 2
  • Hispanic children experienced a 50% increase in poisoning deaths during the same period 2
  • White children have lower rates (9.0 per 100,000) 2

Geographic Disparities

  • Rural areas have 2.6 times higher death rates than urban areas (17.8 vs. 6.8 per 100,000 in most rural vs. most urban counties) 2
  • Death rates increase progressively as rurality increases 2

Firearm-Related Deaths

Firearms are among the top 3 causes of death in American youth, with firearm-related deaths accounting for 28.7% of all injury deaths in 15-19 year-olds and 19.5% in those under 20 years 4

  • The United States has firearm homicide rates 35.7 times higher than other high-income countries for youth 15-24 years 4
  • Firearm suicide rates are 8 times higher in children 5-14 years compared to other high-income countries 4
  • Black males 15-34 years are particularly affected, with firearms being the leading cause of death 4

Economic Impact

  • Deaths from injuries account for more years of potential life lost under 18 years than SIDS, cancer, and infectious diseases combined 1
  • The direct cost of childhood injury exceeds $50 billion annually in the United States 1

Common Pitfalls in Understanding Pediatric Injury Mortality

  • Vital statistics alone underestimate the true burden - death certificate data provide limited information about circumstances compared to multidisciplinary child fatality review teams 4
  • Aggregate trends mask important disparities - while overall injury death rates decreased 11% from 2010-2019, specific subgroups experienced increases 2, 3
  • Age-specific patterns are critical - the leading cause varies dramatically by age, from SIDS in infants to drowning in toddlers to motor vehicle crashes in adolescents 4, 1, 2

References

Guideline

Major Causes of Death in Children Aged 0-18 Years

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Reducing the global burden of childhood unintentional injuries.

Archives of disease in childhood, 2014

Research

Prevention of unintentional childhood injuries.

American family physician, 2006

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.