Management of Contact Dermatitis
Immediate First-Line Treatment
The cornerstone of contact dermatitis management is complete avoidance of the causative irritant or allergen combined with emollients and topical corticosteroids for active inflammation. 1, 2
Identify and Eliminate the Trigger
- Replace all soaps and detergents with emollient substitutes for hand washing and bathing 2
- Common irritants to avoid include water itself (excessive contact), detergents, organic solvents, and in occupational settings: oils, coolants, alkalis, acids, and solvents 2, 3
- For occupational cases, conduct a workplace visit to identify hidden irritants not apparent from history alone—this is critical as many exposures are missed without direct observation 2, 3
Emollient Therapy (Essential for All Cases)
- Apply emollients immediately after every hand wash using two fingertip units per application 2
- Use tube packaging rather than jars to prevent bacterial contamination 2, 3
- "Soak and smear" technique for severe hand involvement: soak hands in plain water for 20 minutes, then immediately apply moisturizer to still-damp skin every night for up to 2 weeks 2
Topical Corticosteroid Protocol
- For body and hands: Apply mid- to high-potency topical corticosteroid (such as triamcinolone 0.1% or clobetasol 0.05%) twice daily for acute flares 3, 4
- For facial lesions: Use only low-potency steroids to minimize risk of skin atrophy 3
- Long-term intermittent use of mometasone furoate has Level I evidence for chronic hand eczema (Strength of recommendation B) 1
- Topical tacrolimus has demonstrated effectiveness in nickel-induced allergic contact dermatitis 1
Systemic Corticosteroids for Extensive Disease
- When allergic contact dermatitis involves >20% body surface area, systemic steroid therapy is required and provides relief within 12-24 hours 4
- For severe rhus (poison ivy) dermatitis: Taper oral prednisone over 2-3 weeks—rapid discontinuation causes rebound dermatitis 4
Protective Measures
- Use rubber or polyvinyl chloride gloves with cotton liners for household tasks, but remove regularly to prevent sweat accumulation that worsens dermatitis 3
- For occupational exposures, match glove type to specific chemical exposure by checking Material Safety Data Sheets for appropriate selection and permeation times 3
Diagnostic Workup for Persistent Cases
- Patients with persistent eczematous eruptions should undergo patch testing (Quality of evidence II.ii, Strength of recommendation A) 1
- Patch test to at least an extended standard series of allergens 1
- Trained personnel should perform day 2 and day 4 readings 1
Second-Line Treatments for Refractory Disease
For steroid-resistant chronic hand dermatitis, second-line options include: 1, 3
- Psoralen plus UVA (PUVA)
- Azathioprine
- Ciclosporin
These treatments have Level I evidence with Strength of recommendation A 1
Critical Pitfalls to Avoid
- Do not use topical corticosteroids for rosacea or perioral dermatitis—these conditions worsen with steroid application 1
- Avoid occlusive dressings with potent topical steroids as they increase systemic absorption and HPA axis suppression 5
- If treatment fails after 7 days, re-evaluate the diagnosis and consider dermatology referral 3