What is the management for contact dermatitis?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: December 5, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Management of Contact Dermatitis

Immediate First-Line Treatment

The cornerstone of contact dermatitis management is complete avoidance of the causative irritant or allergen combined with emollients and topical corticosteroids for active inflammation. 1, 2

Identify and Eliminate the Trigger

  • Replace all soaps and detergents with emollient substitutes for hand washing and bathing 2
  • Common irritants to avoid include water itself (excessive contact), detergents, organic solvents, and in occupational settings: oils, coolants, alkalis, acids, and solvents 2, 3
  • For occupational cases, conduct a workplace visit to identify hidden irritants not apparent from history alone—this is critical as many exposures are missed without direct observation 2, 3

Emollient Therapy (Essential for All Cases)

  • Apply emollients immediately after every hand wash using two fingertip units per application 2
  • Use tube packaging rather than jars to prevent bacterial contamination 2, 3
  • "Soak and smear" technique for severe hand involvement: soak hands in plain water for 20 minutes, then immediately apply moisturizer to still-damp skin every night for up to 2 weeks 2

Topical Corticosteroid Protocol

  • For body and hands: Apply mid- to high-potency topical corticosteroid (such as triamcinolone 0.1% or clobetasol 0.05%) twice daily for acute flares 3, 4
  • For facial lesions: Use only low-potency steroids to minimize risk of skin atrophy 3
  • Long-term intermittent use of mometasone furoate has Level I evidence for chronic hand eczema (Strength of recommendation B) 1
  • Topical tacrolimus has demonstrated effectiveness in nickel-induced allergic contact dermatitis 1

Systemic Corticosteroids for Extensive Disease

  • When allergic contact dermatitis involves >20% body surface area, systemic steroid therapy is required and provides relief within 12-24 hours 4
  • For severe rhus (poison ivy) dermatitis: Taper oral prednisone over 2-3 weeks—rapid discontinuation causes rebound dermatitis 4

Protective Measures

  • Use rubber or polyvinyl chloride gloves with cotton liners for household tasks, but remove regularly to prevent sweat accumulation that worsens dermatitis 3
  • For occupational exposures, match glove type to specific chemical exposure by checking Material Safety Data Sheets for appropriate selection and permeation times 3

Diagnostic Workup for Persistent Cases

  • Patients with persistent eczematous eruptions should undergo patch testing (Quality of evidence II.ii, Strength of recommendation A) 1
  • Patch test to at least an extended standard series of allergens 1
  • Trained personnel should perform day 2 and day 4 readings 1

Second-Line Treatments for Refractory Disease

For steroid-resistant chronic hand dermatitis, second-line options include: 1, 3

  • Psoralen plus UVA (PUVA)
  • Azathioprine
  • Ciclosporin

These treatments have Level I evidence with Strength of recommendation A 1

Critical Pitfalls to Avoid

  • Do not use topical corticosteroids for rosacea or perioral dermatitis—these conditions worsen with steroid application 1
  • Avoid occlusive dressings with potent topical steroids as they increase systemic absorption and HPA axis suppression 5
  • If treatment fails after 7 days, re-evaluate the diagnosis and consider dermatology referral 3

Prognosis Counseling

  • The prognosis for occupational contact dermatitis is poor: only 25% of patients completely recover within 10 years 2, 3
  • 50% have periodic symptoms and 25% have permanent symptoms 2
  • Changing jobs does not guarantee improvement—40% of those who changed occupations showed no improvement 2

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Management of Irritant Contact Dermatitis

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Management of Irritant Contact Dermatitis

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Diagnosis and management of contact dermatitis.

American family physician, 2010

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.