No Natural Supplement is Recommended for Choroid Plexus Tumors
There is no evidence-based natural supplement for treating choroid plexus tumors, and relying on supplements instead of proven medical therapy would be dangerous and potentially fatal. Choroid plexus tumors—whether benign papillomas or malignant carcinomas—require aggressive medical intervention focused on surgical resection, with adjuvant chemotherapy and radiation for carcinomas.
Why Natural Supplements Are Not the Answer
The medical literature on choroid plexus tumors contains zero evidence supporting natural supplements as treatment. The provided evidence focuses exclusively on:
- Surgical resection as the primary treatment modality 1, 2, 3
- Chemotherapy agents (etoposide, cyclophosphamide, carboplatin) for carcinomas 4
- Radiation therapy for incompletely resected carcinomas 1, 2
Evidence-Based Treatment Approach
For Choroid Plexus Papilloma (WHO Grade I)
- Gross total resection is curative with 5-year survival rates of 81% and 10-year survival of 77% 1
- Post-surgical "wait and see" approach is appropriate after complete resection 1
- No adjuvant therapy needed if completely resected 1, 3
For Choroid Plexus Carcinoma (WHO Grade III)
- Radical surgical resection remains the cornerstone, achieving gross total resection in 91.7% of cases 3
- Adjuvant chemotherapy is essential for residual disease, with etoposide showing the highest response rate (17/36 patients) and statistically significant survival benefit 4
- Radiation therapy significantly improves survival in carcinomas, though avoided in children under 3 years due to neurodevelopmental risks 1, 2
- Five-year survival for carcinomas is only 41% even with aggressive treatment 1
Critical Prognostic Factors
Extent of surgical resection is the most important modifiable factor affecting survival in both papillomas (P=0.0005) and carcinomas (P=0.0001) 1. Tumor recurrence occurs in 25% of cases and is significantly associated with subtotal resection (p=0.002) and histological grade (p=0.004) 3.
The Danger of Delay
Choroid plexus carcinomas are WHO grade III malignant tumors with dismal outcomes 4, 5. Mean progression-free survival is only 24.5 months even with optimal treatment 5. Delaying proven medical therapy to pursue unproven natural supplements would allow:
- Tumor growth and increased surgical morbidity
- CNS dissemination (the cause of death in multiple case series) 5
- Loss of the critical window for gross total resection
- Progression from atypical papilloma to carcinoma 5
Any patient with a choroid plexus tumor should immediately consult a neurosurgeon at a center experienced in managing these rare tumors 2, 3. The rarity of these tumors (representing only 1.8% of all brain tumors) necessitates treatment at specialized centers 6.