From the Guidelines
For treating a Guillain-Barré Syndrome (GBS) attack, I recommend starting with intravenous immunoglobulin or plasma exchange as soon as possible after symptoms begin, as these treatments have been shown to be equally effective in treating GBS 1.
Key Considerations
- Respiratory function should be monitored in all patients, as respiratory failure can occur without symptoms of dyspnoea 1.
- Electrophysiological studies and cerebrospinal fluid examinations can aid in diagnosis, but patients with GBS can have normal results in both tests, especially early in the disease course 1.
- The efficacy of repeat treatment in patients who have shown insufficient clinical response is uncertain, but this practice is common in patients who show deterioration after an initial treatment response 1.
Treatment Approach
- Intravenous immunoglobulin and plasma exchange are the only treatments that have been proven to be effective in treating GBS 1.
- Clinical improvement is usually most extensive in the first year after disease onset and can continue for >5 years 1.
- Patients with GBS should be closely monitored for disease progression and potential complications, such as cardiac arrhythmias and blood pressure instability 1.
Additional Recommendations
- Patients with GBS should be admitted to the intensive care unit if they show signs of respiratory failure or other severe complications 1.
- A multidisciplinary approach to care, including neurologists, intensivists, and physical therapists, can help improve outcomes for patients with GBS 1.
From the Research
Giuro Attack Treatment
There are no research papers to assist in answering this question as the provided studies do not mention "Giuro attack" specifically.
Available Information on Seizure Treatment
However, the studies provide information on the treatment of seizures and status epilepticus:
- Benzodiazepines, such as lorazepam and diazepam, are commonly used to treat seizures and status epilepticus 2, 3, 4, 5.
- The choice of benzodiazepine may depend on various factors, including the patient's age, medical history, and the severity of the seizure 3, 4.
- Some studies suggest that lorazepam may be more effective than diazepam in stopping seizures 3, while others found no significant difference between the two 4.
- The timing of benzodiazepine administration is also important, as early administration may lead to vital instability in some patients 5.
- Other anti-seizure medications, such as Levetiracetam, may also be used to treat seizures, and the choice of medication may depend on various factors, including the patient's medical history and the severity of the seizure 6.
Key Points
- Benzodiazepines are commonly used to treat seizures and status epilepticus.
- The choice of benzodiazepine may depend on various factors, including the patient's age and medical history.
- The timing of benzodiazepine administration is important, and early administration may lead to vital instability in some patients.
- Other anti-seizure medications, such as Levetiracetam, may also be used to treat seizures.