How many tablets are in a pack of levonorgestrel (progestin) and ethinyl estradiol (estrogen) 0.15-0.03mg?

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Standard Pack Size for Levonorgestrel-Ethinyl Estradiol Combination Pills

Standard pill packs contain 28 pills total, consisting of 21 to 24 hormone-containing tablets plus 4 to 7 placebo (hormone-free) pills. 1

Pack Configuration Details

The specific levonorgestrel 0.15mg/ethinyl estradiol 0.03mg formulation you're asking about is a monophasic combined oral contraceptive (COC) that follows the standard 28-day pack structure 1:

  • 21 active hormone tablets containing levonorgestrel 0.15mg (150 micrograms) and ethinyl estradiol 0.03mg (30 micrograms) 1
  • 7 placebo tablets for the hormone-free interval 1

Clinical Context

This monophasic formulation (where each active tablet contains the same hormone dose) is commonly recommended as a starting option for adolescents and women seeking contraception 1. The 30 microgram ethinyl estradiol dose with levonorgestrel is specifically mentioned as a preferred initial choice by many adolescent medicine providers 1.

Important Prescribing Considerations

  • The 7-day hormone-free interval (placebo week) is when withdrawal bleeding typically occurs 1
  • For patients with conditions like severe dysmenorrhea, endometriosis, or bleeding disorders, extended-cycle regimens that minimize or eliminate the placebo interval may be more appropriate 1
  • Shorter placebo intervals optimize ovarian suppression and may improve contraceptive effectiveness, particularly in patients who frequently miss pills 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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