From the Research
A sample prescription for probiotics in Canada might include a combination of Lactobacillus acidophilus and Bifidobacterium bifidum, taken as one capsule daily, containing 8.7×10^8 CFU of bifidobacteria and 6.1×10^9 CFU of lactobacilli, as seen in the study by 1. This recommendation is based on the most recent and highest quality study available, which demonstrated the efficacy of this probiotic combination in reducing the severity of clinical manifestations in patients with irritable bowel syndrome and antibiotic-associated diarrhea. Some key points to consider when prescribing probiotics include:
- Starting with the recommended dose on the package and taking them with food to minimize potential digestive discomfort
- Considering higher doses or specific strains for specific health conditions, such as antibiotic-associated diarrhea or irritable bowel syndrome
- Consulting with a healthcare provider for personalized recommendations
- Being aware of the potential benefits of probiotics, including introducing beneficial bacteria to the gut microbiome, which can help with digestive issues, immune function, and potentially mood regulation. The study by 1 provides strong evidence for the use of probiotics in reducing the severity of clinical manifestations in patients with irritable bowel syndrome and antibiotic-associated diarrhea, and its findings can be applied to real-life clinical practice. Other studies, such as 2, 3, 4, and 5, also demonstrate the potential benefits of probiotics, but the study by 1 is the most recent and highest quality, making it the most relevant to clinical practice. In terms of specific products, Align and Florastor are commonly available over-the-counter at pharmacies across Canada, but the combination of Lactobacillus acidophilus and Bifidobacterium bifidum, as seen in the study by 1, may be a more effective option for certain patients. Ultimately, the decision to prescribe probiotics should be based on the individual patient's needs and medical history, and should be made in consultation with a healthcare provider.