What causes a unilateral malar rash?

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Last updated: February 12, 2025View editorial policy

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Differential Diagnosis for Unilateral Malar Rash

  • Single Most Likely Diagnosis
    • Lupus erythematosus: This is the most common cause of a malar rash, which is a characteristic "butterfly-shaped" rash across the cheeks. Although it is typically bilateral, it can occasionally present unilaterally.
  • Other Likely Diagnoses
    • Dermatomyositis: This is an inflammatory disease characterized by skin rash and muscle weakness. The rash can be similar to a malar rash and may be unilateral.
    • Rosacea: A chronic skin condition characterized by facial redness, swelling, and small, pus-filled bumps. It can cause a unilateral malar rash, especially if it is localized to one side of the face.
    • Contact dermatitis: This is a type of skin inflammation caused by contact with irritants or allergens. It can cause a unilateral malar rash if the irritant or allergen comes into contact with one side of the face.
  • Do Not Miss Diagnoses
    • Erythema multiforme: A skin condition characterized by target-shaped lesions, which can be a sign of a life-threatening condition such as Stevens-Johnson syndrome. Although it is typically bilateral, it can occasionally present unilaterally.
    • Cellulitis: A bacterial skin infection that can cause redness, swelling, and warmth of the skin. If left untreated, it can lead to serious complications, such as sepsis.
  • Rare Diagnoses
    • Sarcoidosis: A condition characterized by the growth of granulomas (inflammatory cells) in various parts of the body, including the skin. It can cause a unilateral malar rash, although this is a rare presentation.
    • Granuloma faciale: A rare skin condition characterized by a chronic, inflammatory lesion on the face, which can cause a unilateral malar rash.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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