Treatment of Dry and Cracked Lips and Corners of the Mouth in an Infant Boy
Apply white soft paraffin ointment (petroleum jelly) to the lips every 2 hours, ensure adequate hydration, and evaluate for underlying causes including nutritional deficiencies, candidal infection, or bacterial colonization. 1
Immediate Management
Primary Lip Care
- Apply white soft paraffin ointment (petroleum jelly) to the lips every 2 hours as the cornerstone of treatment, which provides a protective barrier and prevents further moisture loss 1
- Use only animal or plant-based oils such as beeswax, cocoa butter, or lanolin for lip lubrication—avoid petroleum-based products as these cause drying and cracking 1
- Apply emollient liberally and frequently throughout the day, particularly before and after feeding 1
Feeding Modifications
- Apply emollient to pacifiers and bottle teats before each use to reduce friction on already compromised lip tissue 1
- Administer pain relief (paracetamol/acetaminophen) 20 minutes prior to feeding if the infant shows discomfort 1
- Support the infant upright during feeding to minimize lip trauma 1
Evaluation for Underlying Causes
Angular Cheilitis Considerations
Angular cheilitis (cracking at the corners of the mouth) in infants has mixed bacterial and fungal etiology and may indicate underlying disease 2
Key diagnostic steps:
- Take swabs for bacterial and candidal culture from affected areas, particularly if crusting or sloughing is present 1
- Consider nutritional deficiencies (iron, B vitamins, zinc) if the condition persists despite topical treatment 2
- Evaluate for excessive drooling or saliva pooling at mouth corners, which creates a moist environment favoring microbial overgrowth 2
Treatment Based on Culture Results
- If candidal infection confirmed: Consider topical antifungal therapy appropriate for infant age 2
- If bacterial infection present: Appropriate antimicrobial therapy based on culture sensitivities 1
- For severe inflammation in infants: Consider clobetasol propionate 0.05% cream or ointment applied topically to affected areas including lips during acute phase 1
Preventive Measures
Oral Hygiene and Moisture Management
- Clean the mouth daily with warm saline using gentle dabbing technique rather than rubbing 1
- Ensure adequate systemic hydration—dry lips often reflect overall dehydration 3
- Protect lips from harsh environmental conditions (cold, wind, dry air) 3
Feeding Practice Optimization
- Discontinue prolonged bottle use if applicable—bottle feeding beyond 12-24 months increases risk of perioral irritation and dental caries 4
- Wipe the infant's mouth gently after feeding to remove residual milk or formula that can irritate compromised skin 4
- Avoid allowing the infant to sleep with a bottle, which causes prolonged moisture exposure 4
Common Pitfalls to Avoid
Critical errors in management:
- Using petroleum-based lip products, which paradoxically worsen dryness and cracking 1
- Failing to culture persistent lesions, missing treatable infections 1
- Overlooking nutritional deficiencies in infants with recurrent or refractory angular cheilitis 2
- Ignoring the possibility of lip-licking behavior even in infants, which perpetuates the cycle of irritation 3, 5
When to Refer
Immediate referral to pediatric dentist or dermatologist if:
- Lesions persist beyond 2 weeks despite appropriate topical therapy 1
- Severe inflammation with suspected infection develops 1
- Facial swelling of unknown origin accompanies lip lesions 1
- Possible oral abnormality or systemic disease is suspected 1