What are the current trends and recommendations for dental adhesives?

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Last updated: December 8, 2025View editorial policy

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Current Trends in Dental Adhesives

Universal adhesives represent the most significant recent advancement in adhesive dentistry, offering flexibility to use either etch-and-rinse or self-etch modes depending on the clinical situation, though etching enamel prior to application remains recommended for optimal bond strength. 1, 2

Evolution to Universal Adhesive Systems

The dental adhesive landscape has progressed dramatically from early ineffective systems to today's sophisticated universal (multi-mode) adhesives 1, 3. These newer systems fundamentally differ from previous generations by allowing clinicians to choose between:

  • Etch-and-rinse mode - where phosphoric acid is applied first, then rinsed before adhesive application 3
  • Self-etch mode - where the adhesive simultaneously etches and primes the tooth surface without a separate rinsing step 3

This flexibility represents a paradigm shift that simplifies clinical protocols while maintaining effectiveness 1.

Key Technical Considerations by Substrate

Bonding to Enamel

Always etch enamel with phosphoric acid before applying universal adhesives, regardless of the adhesive's "universal" designation 2. The evidence is clear on this point:

  • Etch-and-rinse systems consistently outperform self-etch approaches on enamel 4, 2
  • Pre-etching enamel significantly enhances bond strength even when using universal adhesives 2
  • Acid-etching of enamel has proven reliable for decades because bond strengths reach the internal strength of enamel prism components 5

Bonding to Dentin

For dentin, the choice between modes is more nuanced:

  • Self-etch adhesives may be more suitable for dentin bonding compared to their performance on enamel 4
  • Universal adhesives show no statistically significant difference in dentin bond strength between self-etch and etch-and-rinse modes 2
  • The hydrophilic character of modern adhesives provides higher and faster bond strengths to dentin 5

Critical Application Principles

Regardless of which universal adhesive system you select, these fundamental principles determine success:

  • Ensure complete dryness - The bonding surface must be completely dry before applying adhesive, as moisture prevents proper adhesion 6, 7
  • Minimize adhesive pooling - Apply the least amount of adhesive necessary to avoid excess material that could cause pooling and subsequent complications 6, 8
  • Follow manufacturer protocols - Appropriate clinical handling of the material is as important as the chemistry itself 4

Material Selection Strategy

When selecting among available universal adhesives:

  • Bond strength varies significantly between different universal adhesive brands, even when using the same application mode 2
  • Consider the specific clinical application - different anatomical characteristics of enamel versus dentin have implications for technique and bond quality 4
  • Evaluate the chemistry of the adhesive system, as successful bonding depends on both material properties and clinical technique 4

Clinical Implications for Restoration Longevity

The choice of adhesive system directly impacts restoration outcomes:

  • Careful consideration prevents restoration loss, secondary caries, or pulp damage from bacterial penetration 4
  • Cytotoxicity effects from eluted adhesive components must be considered when selecting bonding procedures 4
  • For implant-supported restorations, choose appropriate resin cement as this plays a crucial role in clinical success 6

Common Pitfalls to Avoid

  • Don't skip enamel etching - Even with "universal" adhesives, enamel etching remains essential for optimal bond strength 2
  • Don't over-apply adhesive - Excess material creates pooling that compromises the restoration 6
  • Don't ignore substrate differences - Enamel and dentin require different considerations despite using the same adhesive system 4

References

Research

Universal adhesives: the next evolution in adhesive dentistry?

Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995), 2015

Research

Current dental adhesives systems. A narrative review.

Current pharmaceutical design, 2012

Guideline

Improving Longevity of Restorations with Adhesive Pooling

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Application of Cyanoacrylate Tissue Adhesive in Wound Care

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

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Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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