What is the youngest age to administer Pedialyte (oral rehydration solution) to an infant?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Article Review Status
Submitted
Under Review
Approved

Last updated: April 4, 2025 • View editorial policy

From the Guidelines

Pedialyte can be given to infants as young as newborns under appropriate circumstances, with the recommendation to offer small amounts frequently, such as 1-2 teaspoons (5-10 mL) every 15-20 minutes, gradually increasing as tolerated, as stated in the 2017 Infectious Diseases Society of America clinical practice guidelines for the diagnosis and management of infectious diarrhea 1. For infants under 1 year old, it is always best to consult with a pediatrician before giving Pedialyte. The solution works by replacing essential electrolytes and fluids lost during diarrhea or vomiting, helping to prevent dehydration. According to the guidelines, reduced osmolarity oral rehydration solution (ORS) is recommended as the first-line therapy of mild to moderate dehydration in infants, children, and adults with acute diarrhea from any cause 1. Some commercially available formulations that can be used as ORS include Pedialyte Liters (Abbott Nutrition) 1. Signs that indicate your infant needs Pedialyte include fewer wet diapers than normal, dry mouth, crying without tears, unusual drowsiness, or irritability. Never substitute homemade solutions or sports drinks for Pedialyte, as these may have improper electrolyte balances that could be harmful to infants. It is essential to note that breastfed infants should continue nursing throughout the illness, and for infants under 6 months, use only unflavored Pedialyte to avoid unnecessary additives 1. In cases of severe dehydration, intravenous rehydration should be considered, and once the patient is rehydrated, maintenance fluids should be administered, replacing ongoing losses in stools from infants, children, and adults with ORS, until diarrhea and vomiting are resolved 1, 2.

From the Research

Oral Rehydration Solutions for Infants

The use of oral rehydration solutions, such as Pedialyte, is a common practice for treating dehydration in infants. According to the studies, oral rehydration therapy can be safely used in infants, including newborns, to treat dehydration caused by diarrhea 3.

Age and Oral Rehydration

The studies do not specify a minimum age for giving infant Pedialyte, but they do provide information on the use of oral rehydration solutions in infants of various ages. For example, one study included infants as young as 2 months old 4, while another study included infants up to 2 years old 5. Another study included infants as young as newborns 3.

Key Findings

  • Oral rehydration therapy was successful in 95% of newborns included in one study 3.
  • Pedialyte was found to be a safe glucose/electrolyte solution for oral rehydration therapy in infants 6.
  • Breastfeeding can be continued during oral rehydration therapy, and additional water may not be necessary 4.
  • Maintenance of breastfeeding and use of oral rehydration therapy at home during acute diarrhea can help prevent dehydration in infants 7.

Considerations

  • The American Academy of Pediatrics recommends oral rehydration therapy as the first line of treatment for mild to moderate dehydration in infants and children.
  • Pedialyte is a commonly used oral rehydration solution that can be given to infants, but it's essential to follow the instructions and consult with a healthcare professional if unsure.
  • Breastfeeding should be continued during oral rehydration therapy, as it provides essential nutrients and helps with hydration.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.